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View Structure Prediction Details

Protein: mtTFB2-PA
Organism: Drosophila melanogaster
Length: 452 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mtTFB2-PA.

Description E-value Query
Range
Subject
Range
gi|54637726, gi|... - gi|54637726|gb|EAL27128.1| GA17767-PA [Drosophila pseudoobscura], gi|125773467|ref|XP_001357992.1| G...
328.0 [0..1] [441..1]

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Predicted Domain #1
Region A:
Residues: [1-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPLRCSWSF ARANYSTKKE LVTRYSGDFP EKLLNRKQKV PTHMYIANSE AAARINQYLE  60
   61 PHFQSSGCDT VMELNSGAGY FTRHLLDRES QFRRIILLES MDHFMPKIQE LHTLYPERVK 120
  121 VRQGDFVNLW KLVYMDKMDG GSRVADLLSD VPQKAFTDDI NMLVFGAVGS YPFFKHLINS 180
  181 LIFQTSLFNL GRCEMILAMP PPIYIHLTCN NEIGYLIYRS TSVLFQILFE HKFIAKVPRE 240
  241 DFLPQQMAYS PTKSSKLGKV QSINPEYLYL VKFTPRRNLH ELCQSQDLPA LWFFIKQNYV 300
  301 SRRNRIIPNL EKWVPGCGPR LIINPKSSES VTPIYPDELP KKLPQYSCQS TTMSTRNYYP 360
  361 GINIYTQFGD LLPSQILTLF SQFRQWPEYG ESSFLASLEN ALLKLETAND EPNLEDGVTL 420
  421 PEEDDAEADE IIEEESPVPA TTPVKRRRKA SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.221849
Match: 1zq9A
Description: Crystal structure of human Dimethyladenosine transferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 1.42049721553167 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 1.07629237539972 bayes_pls_golite062009
transferase activity 1.07321114919891 bayes_pls_golite062009
binding 1.06990970478592 bayes_pls_golite062009
methyltransferase activity 1.06467956103007 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 1.04881630872808 bayes_pls_golite062009
DNA binding 1.03011331296251 bayes_pls_golite062009
nucleic acid binding 0.718731143662013 bayes_pls_golite062009
N-methyltransferase activity 0.619676326387443 bayes_pls_golite062009
protein methyltransferase activity 0.527930488619791 bayes_pls_golite062009
mitochondrial transcription initiation factor activity 0.481383105532041 bayes_pls_golite062009
RNA methyltransferase activity 0.473668177706488 bayes_pls_golite062009
transcription factor binding 0.149382105526243 bayes_pls_golite062009
protein binding 0.0283208412023089 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle