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Protein Overview: MED6-PA, FBpp030...

General Information:
Name(s) found: FBpp0308776 [FlyBase]
MED6-PD / FBpp0291087 [FlyBase]
MED6-PC / FBpp0291086 [FlyBase]
MED6-PA / FBpp0081640 [FlyBase]
MED6-PB / FBpp0081639 [FlyBase]
Description(s) found:
Found 55 descriptions.
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  • type=protein; loc=3R:complement(5592163..5592449,5592510..5592615,5592670..5592844,5592899..5593080); ID=FBpp0308776; name=MED6-PE; parent=FBgn0024330,FBtr0339719; dbxref=FlyBase:FBpp0308776,FlyBase_Annotation_IDs:CG9473-PE; MD5=67a7a672556372b7df018014889b936a; length=249; release=r5.56; species=Dmel; [FlyBase]
  • The gene Mediator complex subunit 6 is referred to in FlyBase by the symbol Dmel\MED6 (CG9473, FBgn0024330). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5591753..5594706. It has the cytological map location 85E8. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription mediator activity; transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene Mediator complex subunit 6 is referred to in FlyBase by the symbol Dmel\MED6 (CG9473, FBgn0024330). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5591753..5594706. It has the cytological map location 85E8. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription mediator activity; transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene Mediator complex subunit 6 is referred to in FlyBase by the symbol Dmel\MED6 (CG9473, FBgn0024330). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5591753..5594706. It has the cytological map location 85E8. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription mediator activity; transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene Mediator complex subunit 6 is referred to in FlyBase by the symbol Dmel\MED6 (CG9473, FBgn0024330). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5591753..5594706. It has the cytological map location 85E8. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription mediator activity; transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 249 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    cytoplasm [IDA]
    mediator complex [IDA][IMP][ISS]
    Biological Process: transcription from RNA polymerase II promoter [IMP][ISS]
    transcription initiation from RNA polymerase II promoter [ISS]
    regulation of transcription from RNA polymerase II promoter [IDA]
    Molecular Function: protein binding [IPI]
    transcription coactivator activity [IDA]
    RNA polymerase II transcription mediator activity [IMP][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRQMTNDH LRLSWHDTQM MATLSPQTVM DYFCRKSNPF YDHMCNNETV RMQRLGPEHL  60
   61 HNMIGLEYIL LHVAEPILYV IRKQHRHNPS EATPIADYYI IGGTVYKAPD LANVINSRIL 120
  121 NTVVNLQSAF EEASSYARYH PNKGYTWDFS SNKVFSDRSK SDKKDANSAK DENSGTLFQK 180
  181 QRVDMLLAEL LRKFPPPIPP MLQNLQQPPP AGDDLNTARN ASEMNNATGP LDIKTEGVDM 240
  241 KPPPEKKSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..173] Pfam 63.187087 No description for PF04934.5 was found. No confident structure predictions are available.
    2 View Details [174..249] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle