YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Aats-trp-PB

General Information:
Name(s) found: Aats-trp-PB / FBpp0081461 [FlyBase]
Description(s) found:
Found 31 descriptions.
SHOW ALL
  • The gene Tryptophanyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-trp (CG9735, FBgn0010803). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5089539..5092670. It has the cytological map location 85D7. There is experimental evidence that it has the molecular function</span>: tryptophan-tRNA ligase activity. There is experimental evidence that it is involved in the biological process</span>: lysosome organization; tryptophanyl-tRNA aminoacylation. 20 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 430 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: lysosome organization [IMP]
    tryptophanyl-tRNA aminoacylation [IDA][ISS]
    Molecular Function: ATP binding [IEA]
    tryptophan-tRNA ligase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADTKETVVE GVEALTLNGK PDAEPVETGT DAQAQEGATA PTEDVVDPWN VASSNDAGVD  60
   61 YDKLIKRFGS SKIDEELIAR FEKITGKPAH HFIRRGMFFS HRDLHTILTL REQGKPFYLY 120
  121 TGRGPSSGSL HVGHLVPFIM TKWLQETFDV PLVIQLTDDE KTLWKDLKVE DAIKLGRENA 180
  181 KDIVAIGFDV NKTFIFNNLE FVGKCPAMYQ NIIRIQKCVT FNQVKGIFGF GDSDIIGKIG 240
  241 FPAAQAAPAI SSTFPFIFGN RKVHCLIPCA IDQDPYFRMT RDVAPRLGFP KCALIHSTFF 300
  301 PALQGAKTKM SASDQNSAVY LTDTPKQIKN KINKYAFSGG RVSVEEHRKL GGVPEVDVSY 360
  361 QLLKFFLEDD AKLEEVRVAY SKGEMLTGEI KKLAVETLTP IVEQHQAARK LITDEVLDKY 420
  421 FELRPLKFGS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..430] PSI-BLAST 129.0 crystal structure of human tryptophanyl-tRNA synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  5.34430928486195 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.01261843164558 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.13743634264647 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.47302762432927 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.161799496958314 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle