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Protein Overview: Ada-PA

General Information:
Name(s) found: Ada-PA / FBpp0081451 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Adenosine deaminase is referred to in FlyBase by the symbol Dmel\Ada (CG11994, FBgn0037661). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4890901..4892025. It has the cytological map location 85C4. Based on sequence similarity, it is predicted to have molecular function</span>: adenosine deaminase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: purine ribonucleoside monophosphate biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 337 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: purine ribonucleoside monophosphate biosynthetic process [IEA]
    Molecular Function: adenosine deaminase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQFLKGLPK VELHAHLNGS LGIKSLCDLG ERLYGTSCKD FLKLCAHFSR FEKDMDACFE  60
   61 KFAFVHELTS TREGLRFATE LAIRDFAEDN VQYVEMRTTP KANENYSRRD YLQIVIDAIK 120
  121 AASETYPEIT VKLLPSINRA EPVDVAEETV SLAVELARAH PNLILGIDLS GNPGKGRFSD 180
  181 FAPILAQARD KGLKLAIHCA EIENPSEVKE MLHFGMSRCG HGTFLTPEDI GQLKQRNIAI 240
  241 ECCLTSNVKS GTVPSLEEHH LKRIMEADAP KVICTDDSGV FDTTLTKEFL IAAETFGLTR 300
  301 EQCIDLTLEA VHHSFASEQE QIQMADRVGN YADILVK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..337] PSI-BLAST 52.0 Crystal Structure of Adenosine Deaminase complexed with FR117016

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • purine nucleoside binding
    		•  5.77008212157543 bayes_pls_golite062009
  • adenosine deaminase activity
    		•  4.58148305437166 bayes_pls_golite062009
  • adenine deaminase activity
    		•  3.70002828902508 bayes_pls_golite062009
  • hydrolase activity
    		•  3.62199995345412 bayes_pls_golite062009
  • dihydropyrimidinase activity
    		•  3.41635858763209 bayes_pls_golite062009
  • deaminase activity
    		•  1.79186203771221 bayes_pls_golite062009
  • catalytic activity
    		•  1.70199291046899 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.60895003474033 bayes_pls_golite062009
  • binding
    		•  1.20793368650496 bayes_pls_golite062009
  • protein binding
    		•  0.928500526896831 bayes_pls_golite062009
  • guanine deaminase activity
    		•  0.861706835095856 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
    		•  0.787370269329878 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.629962267754185 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  0.573107361273483 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.530552339840648 bayes_pls_golite062009
  • DNA binding
    		•  0.462348875991261 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.408989331337656 bayes_pls_golite062009
  • peptidase activity
    		•  0.356051335471361 bayes_pls_golite062009
  • dihydroorotase activity
    		•  0.203044795244555 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle