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Protein Overview: lds-PA

General Information:
Name(s) found: lds-PA / FBpp0081255 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene lodestar is referred to in FlyBase by the symbol Dmel\lds (CG2684, FBgn0002542). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3746156..3750211. It has the cytological map location 84E5. There is experimental evidence that it has the molecular function</span>: DNA-dependent ATPase activity. There is experimental evidence that it is involved in the biological process</span>: transcription termination. 22 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1061 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    Biological Process: transcription termination [IDA]
    termination of RNA polymerase II transcription [ISS]
    Molecular Function: ATP binding [IEA]
    DNA binding [IEA]
    DNA-dependent ATPase activity [IDA][ISS]
    RNA polymerase II transcription termination factor activity [ISS]
    helicase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSENSEYYS DKEEDSVVNN SSLGRSRKSS RLSKSSRLSK SSRPSSAGVV IDETQSEEEE  60
   61 SQSSETAESE KSDESDNSQN SQESEDSEDD SVRPSARNTK RKPLGIPSDS EDEEDELEQR 120
  121 ALSPSTRMSI TGVRPQDLSD DDSEIEYSDE VQEGPTEAPT AEAVVPRYTT QFAGNIQNDL 180
  181 HSTIGAADSE VLDDSSGSDV LILSNKETPI EILSSTDDDA TTNKENMSGP PFERPSKSLS 240
  241 PRSSAGASVV KTSKNLSQPT IQAVLKQKTS PAAPRRSRIK SEDQKVVSQV VYDEEMRKLA 300
  301 EKRVQVSDAE KLFEKVAHKL PDKGSQIMKR IDTLRRELAM DEQWISALRV QQSNVPAVRV 360
  361 VKPTLNPPRA PSIDTLDWDE LSEAVNEIKP VYTGAQGMAT FNNQKALTLE SLKDLHVSLE 420
  421 DLPGPEVLAE DPVGLKVSLM NHQKHALAWM SWRERKLPRG GILADDMGLG KTLTMISSVL 480
  481 ACKNGQEMSE GKDESSDSDS EDDKNKKRKS VTGWKSKGRK DTRRGGTLVV CPASLLRQWE 540
  541 SEVESKVSRQ KLTVCVHHGN NRETKGKYLR DYDIVVTTYQ IVAREHKSLS AVFGVKWRRI 600
  601 ILDEAHVVRN HKSQSSLAVC DLRGKYRWAL TGTPIQNKEL DVYALLKFLR CSPFDDLHTW 660
  661 KKWIDNKSAG GQNRLNLLMK SLMLRRTKAQ LQSDGKLNSL PNKELRLIEI SLDKEEMNVY 720
  721 QTVMTYSRTL FAQFLHQRAE RETDFNYRSD ANKPTYNQIK DPNGAYYKMH EKFARMAGSK 780
  781 KEVKSHDILV LLLRLRQICC HPGLIDAMLD GEESQTMGDH SSDSDTPEID LLAQLNKLAI 840
  841 TDTSTDGQQS VANAGDDGPP LLPDEARIAK ASKNLLKRSN PVFNLHRPSS KINMVIQILK 900
  901 TSILKSSDDK AIVVSQWTSV LDILRDHLSK DGVATLSLNG TIPVKNRQDI VNEFNDRNNQ 960
  961 KRVLLLSLTA GGVGLNLIGA NHLLLLDLHW NPQLEAQAQD RIYRVGQKKN VIIYKFMCVD1020
 1021 TVEQRIKGLQ DKKLDLADGV LTGAKVSSKL TIDDLKGLFG M

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] deduced N/A No confident structure predictions are available.
    2 View Details [203..430] deduced N/A No confident structure predictions are available.
    3 View Details [431..900] PSI-BLAST 47.221849 Sulfolobus solfataricus SWI2/SNF2 ATPase core in complex with dsDNA
    4 View Details [901..994] PSI-BLAST 17.39794 Initiation factor 4a
    5 View Details [995..1061] PSI-BLAST 49.69897 Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle