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Protein Overview: gi|17737813, gi|...

General Information:
Name(s) found: gi|7298805 [NCBI NR]
gi|17737813 [NCBI NR]
Description(s) found:
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  • gi|7298805|gb|AAF54014.1| alpha-Esterase-9, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|17737813|ref|NP_524258.1| alpha-Esterase-9, isoform B [Drosophila melanogaster] [NCBI NR]
  • >CG1128-PB translation from_gene[CG1128 alpha-Est9 FBgn0015577] seq_release:3 mol_weight=63671 cds_boundaries:(3R:3,320,815..3,323,105[-]) aa_length:554 transcript_info:[CG1128-RB seq_release:3] gene_info:[gene symbol:alpha-Est9 FBgn0015577 gene_bounda [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VIB0) Alpha-EST9 protein [DrosMelano7227.FASTAC.txt]
  • (AE003671) alpha-Est9 gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG1128-PB, isoform B [Drosophila melanogaster]gi|17737813|ref|NP_524258.1| CG1128-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(3320793..3321257,3321655..3322391,3322446..3322596,3322775..3323086); ID=FBpp0081080; name=alpha-Est9-PB; parent=FBgn0015577,FBtr0081556; dbxref=FlyBase:FBpp0081080,FlyBase_Annotation_IDs:CG1128-PB,GB_protein:AAF54014.1,REF [fly-100309-contam.fasta]
  • alpha-Esterase-9 CG1128-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG1128-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(3320793..3321257,3321655..3322391,3322446..3322596,3322775..3323086); ID=FBpp0081080; name=alpha-Est9-PB; parent=FBgn0015577,FBtr0081556; dbxref=FlyBase:FBpp0081080,FlyBase_Annotation_IDs:CG1128-PB,GB_protein:AAF54014.1,REFSEQ:NP_524258,GB_protein:AAF54014; MD5=a05d1295da2ccc58be4a13cf1dc0dc10; length=554; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(3320793..3321257,3321655..3322391,3322446..3322596,3322775..3323086); ID=FBpp0081080; name=alpha-Est9-PB; parent=FBgn0015577,FBtr0081556; dbxref=FlyBase:FBpp0081080,FlyBase_Annotation_IDs:CG1128-PB,GB_protein:AAF54014.1,REFSEQ:NP_524258,GB_protein:AAF54014; MD5=a05d1295da2ccc58be4a13cf1dc0dc10; length=554; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Alpha-Esterase-9, isoform B OS=Drosophila melanogaster GN=alpha-Est9 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 554 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: carboxylesterase activity [ISS][NAS]
    cholinesterase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDFKVQQRR YRTSEKTVVS TTYGPIKGVK RKSIYGQSYF SFERIPFAKP PVGELRYKAP  60
   61 QPPEVWTEVR SCTSQGPKPL QKHFVFEMTD GSEDCLYLNV YTKNLYPTKP MPVMVWIYGG 120
  121 GFQFGEASRE CYSPDYLLRE DVVVISINYR LGPLGFLCLD DPELDVPGNA GLKDQVLALR 180
  181 WVKANCSRFG GDSANITIFG DSAGSASVHY MMITEQTHGL FHKAICMSGN TLSPWAVTPQ 240
  241 RNWPYRLAVQ AGYAGENNTR DVWEFLKNAK GSEIIKANGE LCIDEEKKER IGFSFGPVIE 300
  301 PYVTSHCVVP KKPIEMMRTA WSNNIPLIIG GVSNEGLLLY SETKTNPKCL NELDDCRFVV 360
  361 PIELNMDRES ALCREYGDQL RQCYYGDKTP SLDTLHEYLQ MVSHEYFWFP IYRTVLSRLQ 420
  421 YARSAPTYLY RFDFDSKHFN HLRILSCGKK VRGTCHGDDL SYLFYNSLAR KLKNHTREYK 480
  481 CIERLVGLWT HFAACGNPNF DPEQEDLWQP VDPAAVEKHQ LKCLNISDEL KVIDVPDLKK 540
  541 LMVWESFFRR DELL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..554] PSI-BLAST 121.0 Mammalian carboxylesterase (liver carboxylesterase I)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetylcholinesterase activity
    		•  6.01557374116734 bayes_pls_golite062009
  • juvenile hormone epoxide hydrolase activity
    		•  5.69212503305375 bayes_pls_golite062009
  • epoxide hydrolase activity
    		•  4.54228071084398 bayes_pls_golite062009
  • ether hydrolase activity
    		•  3.98161932704074 bayes_pls_golite062009
  • cholinesterase activity
    		•  3.53190978140684 bayes_pls_golite062009
  • hydrolase activity, acting on ether bonds
    		•  3.22022434415297 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  3.19190626066707 bayes_pls_golite062009
  • laminin-1 binding
    		•  2.61620056180634 bayes_pls_golite062009
  • choline binding
    		•  2.44944581139315 bayes_pls_golite062009
  • acetylcholine binding
    		•  2.15366394064412 bayes_pls_golite062009
  • carboxylesterase activity
    		•  2.10340684157921 bayes_pls_golite062009
  • lipase activity
    		•  1.95656432876646 bayes_pls_golite062009
  • hydrolase activity
    		•  1.89798820741335 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  1.63586830236611 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • binding
    		•  0.978846093152455 bayes_pls_golite062009
  • peptidase activity
    		•  0.946698616106528 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  0.92549140936125 bayes_pls_golite062009
  • protein binding
    		•  0.890384359682543 bayes_pls_golite062009
  • receptor binding
    		•  0.845720597560984 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.786172015267385 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.527527404338 bayes_pls_golite062009
  • acylglycerol lipase activity
    		•  0.345658974420231 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.33062249657108 bayes_pls_golite062009
  • phospholipase activity
    		•  0.1336535306364 bayes_pls_golite062009
  • triglyceride lipase activity
    		•  0.05324087110088 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle