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Protein Overview: corto-PA, FBpp03...

General Information:
Name(s) found: FBpp0311362 [FlyBase]
FBpp0300442 [FlyBase]
FBpp0300441 [FlyBase]
FBpp0300440 [FlyBase]
corto-PA / FBpp0078485 [FlyBase]
Description(s) found:
Found 47 descriptions.
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  • type=protein; loc=3R:complement(910095..911747); ID=FBpp0311362; name=corto-PE; parent=FBgn0010313,FBtr0345141; dbxref=FlyBase:FBpp0311362,FlyBase_Annotation_IDs:CG2530-PE; MD5=e18709887498f95158fc5a9826ebec5b; length=550; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:complement(910095..911747); ID=FBpp0300442; name=corto-PD; parent=FBgn0010313,FBtr0308120; dbxref=FlyBase:FBpp0300442,FlyBase_Annotation_IDs:CG2530-PD,REFSEQ:NP_001246923,GB_protein:AFH06242; MD5=e18709887498f95158fc5a9826ebec5b; length=550; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:complement(910095..911747); ID=FBpp0300441; name=corto-PC; parent=FBgn0010313,FBtr0308119; dbxref=FlyBase:FBpp0300441,FlyBase_Annotation_IDs:CG2530-PC,REFSEQ:NP_001246922,GB_protein:AFH06241; MD5=e18709887498f95158fc5a9826ebec5b; length=550; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:complement(910095..911747); ID=FBpp0300440; name=corto-PB; parent=FBgn0010313,FBtr0308118; dbxref=FlyBase:FBpp0300440,FlyBase_Annotation_IDs:CG2530-PB,REFSEQ:NP_001246921,GB_protein:AFH06240; MD5=e18709887498f95158fc5a9826ebec5b; length=550; release=r5.56; species=Dmel; [FlyBase]
  • The gene corto is referred to in FlyBase by the symbol Dmel\corto (CG2530, FBgn0010313). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:909343..912408. It has the cytological map location 82E7. There is experimental evidence that it has the molecular function</span>: protein binding; identical protein binding; protein homodimerization activity. It is reported to be involved in the biological process</span>: chromatin silencing. 25 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; nervous system; adult external prothorax; embryonic/larval hemocoel; metatarsus; hemocyte; cell part; podocyte; endocrine system; imaginal precursor; external compound sense organ; antennal segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 550 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    polytene chromosome [IDA]
    centrosome [NAS]
    PRC1 complex [IPI]
    ESC/E(Z) complex [IPI]
    Biological Process: chromatin silencing [IC]
    Molecular Function: identical protein binding [IPI]
    protein binding [IPI][TAS]
    protein homodimerization activity [IPI]
    RNA polymerase II transcription factor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMAACYANY DMSSLSHGMS ALSALQQQQQ QQQQQHSQTQ QQHHHQQQQQ HMYHAAVAAH  60
   61 QQQLLQQQQQ QQHHRHHHQP ANTSSSSNSR HSHAAATQTQ VAAAVANSRQ QQQQQQQQQQ 120
  121 QQQQQQTASS NSNAAPAPSP QKDYSIPLHV DCSVEYELPN QPKPPAGQRV EPLLMIHPCY 180
  181 FRKMESQRRS PFVNNMHATA RAVSSSSLSS GAALGGGGSG AAVATAPSSS AARRGARAAT 240
  241 SAQQQQQQQQ RYQQQQQQLR QQHQQMSQMS QQAHYPQQQS SLVRQHQQQQ QQQQQQQRAS 300
  301 SNQSQRQSQS QSQSQSHAAN SAAAAAAQAS IAAAAAGQWD QLAALAARTA LTPHHMLHPH 360
  361 SHYAAKGSGG GAGGGKRDAM ISGSYGQTAV ASGKLQQSQV QQQQPQQQQQ HCLPPPPWDA 420
  421 TSMLMDRSPM ATVPSNYQAG PDTNPMRLYS ATPTAGAASG GSASVGGGGA VSGAGATGAV 480
  481 NTATDKLSGK YRQYLRSQRM HPYAAAASLN LAAAAAAAGQ TSFVPFSSAA TAVAATPTFQ 540
  541 HLPQISCYNV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..351] PSI-BLAST 11.30103 Heavy meromyosin subfragment
    2 View Details [352..417] deduced N/A No confident structure predictions are available.
    3 View Details [418..550] MSA 1.205969 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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