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Protein Overview: growl-PA

General Information:
Name(s) found: growl-PA / FBpp0078561 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene growl is referred to in FlyBase by the symbol Dmel\growl (CG14648, FBgn0037245). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:228771..232914. It has the cytological map location 82A6. It is reported to have molecular function</span>: RNA binding. There is experimental evidence that it is involved in the biological process</span>: oocyte dorsal/ventral axis specification. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 545 amino acids

    Gene Ontology:
    Cellular Component: catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    Biological Process: folic acid and derivative biosynthetic process [IEA]
    oocyte dorsal/ventral axis specification [IGI][IMP]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: ATP binding [IEA]
    RNA binding [NAS]
    5-formyltetrahydrofolate cyclo-ligase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDQSNAAPA VAAENGGNTA QEVSSTTQPI EPTKRSLRVQ TWKKIQEGKV GIGFNNIFNR  60
   61 IPSFVGADKA AALFANEEEF KKAQHIKVNI DRVLHEFKEL ALLADKSVYL PSTRESSALC 120
  121 LKVDVLADAT EEQKKEALRV QDIQKFRSEI GLDSGLKLDI VVIGSVVVSR EGYRIGRGNG 180
  181 FADLDIGLLI ELGAITPKTI IVTIVHDMQV VDSLPPNLFQ KYDTPVDIIA TPTEIIRVPK 240
  241 RLSFPNGVYW ELLSERRLKI LPVLQQLKER EEKAGKSISL KEEDTDVEQH QNNRRRRGPV 300
  301 RRRIQRGNPG RTTSQTDNEQ PQGETAQKRT PRRKGRFVNR RRRTTKSEGD QSGVEAGAKT 360
  361 DDRKLPEAGT DERRSKKNKN SDFCIKLTNL SRDIRVKDLK SELRKRECTP MSISWKGHFG 420
  421 KCFLHFGNRK GVPSTQDDMD KVLKSLNDLS LTITTGGETA PAAAAGEGGE KAESAETATP 480
  481 VQTKTILVNV ELIQFGEKKS ASSTGANAGA GEDGKADAQN GGEAVTVAGG DVGGARIEAV 540
  541 DTTTV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..223] PSI-BLAST 41.522879 X-Ray structure of Northeast Structural Genomics target SR44
    2 View Details [224..371] deduced N/A No confident structure predictions are available.
    3 View Details [372..468] PSI-BLAST 27.0 No description for 2e5jA was found.
    4 View Details [469..545] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle