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Catalysis of the ligation of two substances via a carbon-nitrogen bond to form a heterocyclic product, with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 5-formyltetrahydrofolate cyclo-ligase activity
Acc: GO:0030272
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate.
Synonyms:
  • 5-formyltetrahydrofolate cyclo-ligase (ADP-forming)
  • methenyl-THF synthetase activity
  • 5-formyltetrahydrofolate cyclodehydrase
  • formyltetrahydrofolic cyclodehydrase activity
  • 5,10-methenyltetrahydrofolate synthetase activity
  • GO:0019006
  • 5-Formyltetrahydrofolate cyclodehydrase activity
Proteins in PDR annotated with:
   This term: 20 [Search]
   Term or descendants: 20 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030272 - 5-formyltetrahydrofolate cyclo-ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle