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Protein Overview: MP1-PA

General Information:
Name(s) found: MP1-PA / FBpp0078543 [FlyBase]
Description(s) found:
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  • gi|5052512|gb|AAD38586.1|AF145611_1 BcDNA.GH02921 [Drosophila melanogaster] [NCBI NR]
  • gi|28571479|ref|NP_649450.3| melanization protease 1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|28381111|gb|AAF52151.3| melanization protease 1, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene Melanization Protease 1 is referred to in FlyBase by the symbol Dmel\MP1 (CG1102, FBgn0027930). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:133630..135559. It has the cytological map location 82A3. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: melanization defense response. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG1102-PA translation from_gene[CG1102 BEST:GH02921 FBgn0027930] seq_release:3 mol_weight=43705 cds_boundaries:(3R:133,708..135,337[+]) aa_length:390 transcript_info:[CG1102-RA seq_release:3] gene_info:[gene symbol:BEST:GH02921 FBgn0027930 gene_bounda [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9Y157) BEST:GH02921 protein [DrosMelano7227.FASTAC.txt]
  • (AAF52151) CG1102-PA [DrosMelano7227.FASTAC.txt]
  • (AE003606) BEST:GH02921 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG1102-PA [Drosophila melanogaster]gi|5052512|gb|AAD38586.1| BcDNA.GH02921 [Drosophila melanogaster]gi|28571479|ref|NP_649450.3| CG1102-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(133709..133778,133986..134149,134342..134555,134617..135341); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,REFSEQ:NP_649450,GB_protein:AAF52151; MD5=5422 [fly-100309-contam.fasta]
  • Melanization Protease 1 CG1102-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG1102-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • BcDNA.GH02921 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(133709..133778,133986..134149,134342..134555,134617..135341); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,REFSEQ:NP_649450,GB_protein:AAF52151; MD5=5422fe760aa23a8c0fbb64e47397d341; length=390; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(133709..133778,133986..134149,134342..134555,134617..135341); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,GB_protein:AAF52151,REFSEQ:NP_649450; MD5=5422fe760aa23a8c0fbb64e47397d341; length=390; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • BcDNA.GH02921 OS=Drosophila melanogaster GN=MP1 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(133709..133778,133986..134149,134342..134555,134617..135341); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,GB_protein:AAF52151,REFSEQ:NP_649450,FlyMine:FBpp0078543,modMine:FBpp0078543; MD5=5422fe760aa23a8c0fbb64e47397d341; length=390; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(4307987..4308056,4308264..4308427,4308620..4308833,4308895..4309619); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,GB_protein:AAF52151,REFSEQ:NP_649450,FlyMine:FBpp0078543,modMine:FBpp0078543; MD5=5422fe760aa23a8c0fbb64e47397d341; length=390; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(4307987..4308056,4308264..4308427,4308620..4308833,4308895..4309619); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,GB_protein:AAF52151,REFSEQ:NP_649450,FlyMine:FBpp0078543,modMine:FBpp0078543; MD5=5422fe760aa23a8c0fbb64e47397d341; length=390; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of B7Z0T0, BcDNA.GH02921 OS=Drosophila melanogaster GN=MP1 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0078543 type=protein; loc=3R:join(4307987..4308056,4308264..4308427,4308620..4308833,4308895..4309619); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,GB_protein:AAF52151,REFSEQ:NP_649450,FlyMine:FBpp0078543,modMine:FBpp0078543; MD5=5422fe760aa23a8c0fbb64e47397d341; length=390; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(4307987..4308056,4308264..4308427,4308620..4308833,4308895..4309619); ID=FBpp0078543; name=MP1-PA; parent=FBgn0027930,FBtr0078903; dbxref=FlyBase_Annotation_IDs:CG1102-PA,FlyBase:FBpp0078543,GB_protein:AAF52151,REFSEQ:NP_649450,UniProt/TrEMBL:Q9Y157,FlyMine:FBpp0078543,modMine:FBpp0078543; MD5=5422fe760aa23a8c0fbb64e47397d341; length=390; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 390 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA][NAS]
    defense response [NAS]
    melanization defense response [IMP][NAS]
    Molecular Function: serine-type endopeptidase activity [IEA][ISS][NAS]
    serine-type peptidase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPHFFFTVL WMLLMGTSST YAQEIFGYCR TPDENSGTCI NLRECGYLFE LLQSEEVTEQ  60
   61 DRRFLQASQC GYRNGQVLIC CANSRMRNQQ PQWGNHPQPT QTTKPTKRSG TKLLPMAPNC 120
  121 GENFGDRVVG GNETTKREFP WMALIEYTKP GNVKGHHCGG SLINHRYVLT AAHCVSAIPS 180
  181 DWELTGVRLG EWDASTNPDC TVGKNGRRDC NEPYVDYPVE ERIPHPQYPG NSRDQLNDIA 240
  241 LLRLRDEVQY SDFILPVCLP TLASQHNNIF LGRKVVVAGW GRTETNFTSN IKLKAELDTV 300
  301 PTSECNQRYA TQRRTVTTKQ MCAGGVEGVD SCRGDSGGPL LLEDYSNGNS NYYIAGVVSY 360
  361 GPTPCGLKGW PGVYTRVEAY LNWIENNVRA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] PSI-BLAST 12.0 Factor X, N-terminal module
    2 View Details [114..390] PSI-BLAST 55.522879 No description for 2olgA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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