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Protein Overview: DhpD-PA

General Information:
Name(s) found: DhpD-PA / FBpp0078625 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Dihydropterin deaminase is referred to in FlyBase by the symbol Dmel\DhpD (CG18143, FBgn0261436). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:53106..54971. It has the cytological map location 82A1. There is experimental evidence that it has the molecular function</span>: dihydropterin deaminase activity; guanine deaminase activity. There is experimental evidence that it is involved in the biological process</span>: dihydropteridine metabolic process; eye pigment biosynthetic process; guanine metabolic process. 5 alleles are reported. The phenotype of these alleles is annotated with: pigment cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 448 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: guanine metabolic process [IMP]
    eye pigment biosynthetic process [IMP]
    dihydropteridine metabolic process [IDA][IMP]
    Molecular Function: zinc ion binding [IEA]
    guanine deaminase activity [IDA][ISS]
    dihydropterin deaminase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATVFLGTVV HTKSFSEFES FEGGFLAVDD AGKIIGVGQD YHAWASSNPA HAKGLTEVHL  60
   61 SDYQFLMPGF VDCHIHAPQF AQLGLGLDMP LLDWLNTYTF PLEAKFSNHQ YAQQVYQGVV 120
  121 EATLRCGTTL ASYFATNHLE STLTLAREAV RQGQRALIGK VCSNCNSPEF YVETAEESVS 180
  181 ATLAFVEGVR KLGSPMVMPT ITPRFALSCS KELLKSLGDI AKRFDLHIQS HISENLEEIE 240
  241 MVKGIFKTSY AGAYDEAGLL TNKTVLAHGV HLEDDEVALL KVRGCSVAHC PTSNTMLSSG 300
  301 LCDVQRLVSG GVSVGLGTDV SGGNSVSIQD VLLRALDVSK HLDFFKKQNI RGTGVSKTQD 360
  361 FNYHQLKYKQ ALYLATLGGA KALSLDHLTG NFALGKDFDA LLVDVSVVDK PLRRLSVDEL 420
  421 VEKFIYTGSD RNIVEVFVAG KRIKQGYQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..448] PSI-BLAST 62.221849 No description for 2uz9A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • guanine deaminase activity
    		•  3.78802420851729 bayes_pls_golite062009
  • hydrolase activity
    		•  3.06979421893431 bayes_pls_golite062009
  • adenine deaminase activity
    		•  1.87830487335945 bayes_pls_golite062009
  • deaminase activity
    		•  1.79186203771221 bayes_pls_golite062009
  • catalytic activity
    		•  1.70199291046899 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.60895003474033 bayes_pls_golite062009
  • dihydropyrimidinase activity
    		•  1.51712244686012 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
    		•  0.787370269329878 bayes_pls_golite062009
  • binding
    		•  0.771164376899668 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.629962267754185 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  0.573107361273483 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.506159010274668 bayes_pls_golite062009
  • DNA binding
    		•  0.462348875991261 bayes_pls_golite062009
  • peptidase activity
    		•  0.370872229900721 bayes_pls_golite062009
  • dihydroorotase activity
    		•  0.203044795244555 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle