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Protein Overview: frc-PA, frc-PB

General Information:
Name(s) found: frc-PB / FBpp0289098 [FlyBase]
frc-PA / FBpp0074990 [FlyBase]
Description(s) found:
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  • gi|7293986|gb|AAF49343.1| fringe connection, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|221331235|ref|NP_001137962.1| fringe connection, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|220902622|gb|ACL83317.1| fringe connection, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|21744285|gb|AAM76201.1| RH08077p [Drosophila melanogaster] [NCBI NR]
  • gi|20140692|sp|Q95YI5.2|US74C_DROME RecName: Full=UDP-sugar transporter UST74c; AltName: Full=Protein fringe connection [NCBI NR]
  • gi|17647441|ref|NP_524126.1| fringe connection, isoform A [Drosophila melanogaster] [NCBI NR]
  • (Q95YI5) UDP-sugar transporter UST74c (Fringe connection protein) [Swiss-Prot]
  • UDP-sugar transporter UST74c OS=Drosophila melanogaster GN=frc PE=1 SV=2 [Swiss-Prot]
  • The gene fringe connection is referred to in FlyBase by the symbol Dmel\frc (CG3874, FBgn0042641). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17420395..17426288. It has the cytological map location 74B4-74C1. There is experimental evidence that it has the molecular function</span>: UDP-galactose transmembrane transporter activity; UDP-glucuronic acid transmembrane transporter activity; antiporter activity; UDP-N-acetylglucosamine transmembrane transporter activity; UDP-glucose transmembrane transporter activity; UDP-xylose transmembrane transporter activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: pyrimidine nucleotide-sugar transport; nucleotide-sugar transport; anatomical structure development; transport; organ development; carbohydrate transport; embryonic pattern specification; sensory organ development; embryonic development; organ morphogenesis. 21 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: adult segment; organ system; peripheral nervous system; external compound sense organ; nervous system; adult mesothoracic segment; postalar bristle; cuticle; embryonic segment; primordium; antennal segment. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG3874-PA translation from_gene[CG3874 frc FBgn0042641] seq_release:3 mol_weight=41183 cds_boundaries:(3L:17,380,736..17,381,854[-]) aa_length:373 transcript_info:[CG3874-RA seq_release:3] gene_info:[gene symbol:frc FBgn0042641 gene_boundaries:(3L:17, [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003524) CG3874 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG3874-PA [Drosophila melanogaster]gi|21744285|gb|AAM76201.1| RH08077p [Drosophila melanogaster]gi|17647441|ref|NP_524126.1| CG3874-PA [Drosophila melanogaster]gi|20140692|sp|Q95YI5|US74_DROME UDP-sugar transporter UST74c (Fringe connection protein) [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343; MD5=4ed80082177ac1fe8 [fly-100309-contam.fasta]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317; MD5=4ed80082177ac1fe8c147f8763873d99; le [fly-100309-contam.fasta]
  • CG3874-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • fringe connection CG3874-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • UDP-sugar transporter UST74c (Protein fringe connection) [nr-271106-contam.fasta]
  • RH08077p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Fringe connection, isoform B OS=Drosophila melanogaster GN=frc PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343,FlyMine:FBpp0074990,modMine:FBpp0074990; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:complement(17424954..17426075); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343,FlyMine:FBpp0074990,modMine:FBpp0074990; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343,FlyMine:FBpp0074990,modMine:FBpp0074990; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q95YI5, Fringe connection, isoform B OS=Drosophila melanogaster GN=frc PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0074990 type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343,FlyMine:FBpp0074990,modMine:FBpp0074990; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0289098 type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0074990; name=frc-PA; parent=FBgn0042641,FBtr0075228; dbxref=FlyBase:FBpp0074990,FlyBase_Annotation_IDs:CG3874-PA,GB_protein:AAF49343.1,REFSEQ:NP_524126,GB_protein:AAF49343,UniProt/Swiss-Prot:Q95YI5,FlyMine:FBpp0074990,modMine:FBpp0074990; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:complement(17431854..17432975); ID=FBpp0289098; name=frc-PB; parent=FBgn0042641,FBtr0299820; dbxref=FlyBase:FBpp0289098,FlyBase_Annotation_IDs:CG3874-PB,REFSEQ:NP_001137962,GB_protein:ACL83317,UniProt/Swiss-Prot:Q95YI5; MD5=4ed80082177ac1fe8c147f8763873d99; length=373; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 373 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [NAS]
    Biological Process: UDP-glucose transport [IDA]
    UDP-galactose transport [IDA]
    Notch receptor processing [NAS]
    pyrimidine nucleotide-sugar transport [NAS]
    embryonic pattern specification [IMP]
    UDP-xylose transport [IDA]
    imaginal disc-derived wing morphogenesis [IMP]
    segment polarity determination [IMP]
    imaginal disc pattern formation [IMP]
    sensory organ development [IMP]
    compound eye morphogenesis [IMP]
    UDP-N-acetylglucosamine transport [IDA]
    UDP-glucuronic acid transport [IDA]
    Molecular Function: [NOT]UDP-galactose transmembrane transporter activity [IDA]
    [NOT]GDP-mannose transmembrane transporter activity [IDA]
    pyrimidine nucleotide sugar transmembrane transporter activity [NAS]
    antiporter activity [IDA]
    [NOT]UDP-glucose transmembrane transporter activity [IDA]
    UDP-N-acetylglucosamine transmembrane transporter activity [IDA]
    UDP-glucuronic acid transmembrane transporter activity [IDA]
    UDP-xylose transmembrane transporter activity [IDA]
    [NOT]GDP-fucose transmembrane transporter activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMSRGGNTT LDLQPLLAES DVGNRELEEK MGGSADRSSL LDGSGSKELS HREREDSALF  60
   61 VKKIGSALFY GLSSFMITVV NKTVLTSYHF PSFLFLSLGQ LTASIVVLGM GKRLKLVNFP 120
  121 PLQRNTFAKI FPLPLIFLGN MMFGLGGTKT LSLPMFAALR RFSILMTMLL ELKILGLRPS 180
  181 NAVQVSVYAM IGGALLAASD DLSFNMRGYI YVMITNALTA SNGVYVKKKL DTSEIGKYGL 240
  241 MYYNSLFMFL PALALNYVTG NLDQALNFEQ WNDSVFVVQF LLSCVMGFIL SYSTILCTQF 300
  301 NSALTTTIVG CLKNICVTYL GMFIGGDYVF SWLNCIGINI SVLASLLYTY VTFRRKRAPD 360
  361 KQDHLPSTRG ENV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle