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Protein Overview: Syx8-PA

General Information:
Name(s) found: Syx8-PA / FBpp0075124 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Syntaxin 8 is referred to in FlyBase by the symbol Dmel\Syx8 (CG4109, FBgn0036643). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16579208..16580199. It has the cytological map location 73A10. Based on sequence similarity, it is predicted to have molecular function</span>: SNAP receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle docking during exocytosis; neurotransmitter secretion; vesicle-mediated transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 232 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISS]
    Biological Process: synaptic vesicle docking during exocytosis [ISS]
    vesicle-mediated transport [ISS]
    neurotransmitter secretion [ISS]
    Molecular Function: SNAP receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALVDHDSWD IEYEGCERLR HQLLVYLNQR QQLNPRTSQF VQLTSSIQTG IEQLAKDMKH  60
   61 LKVVLDNAIT WETSPEEELQ QRRIDWDRLT SQLREIREKF ANSSRSNVPA ASGSAWQDQD 120
  121 LGPGHSNSSR NTALDVEALK QKKTEMLAQQ NEGLEVLSAT LSRQRQLATQ LGNEVEDQNN 180
  181 ILDNLANAMD RVETGVQRET QSIGQVNRRD STWGYWLVII ALFVAIIVVV FV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..232] PSI-BLAST 26.69897 Syntaxin 1A N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • SNAP receptor activity
    		•  3.50393203740159 bayes_pls_golite062009
  • binding
    		•  2.56277612413299 bayes_pls_golite062009
  • transporter activity
    		•  1.74189664015129 bayes_pls_golite062009
  • extracellular ligand-gated ion channel activity
    		•  1.54368755758216 bayes_pls_golite062009
  • excitatory extracellular ligand-gated ion channel activity
    		•  1.54368755758216 bayes_pls_golite062009
  • protein binding
    		•  1.51700626946713 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.49085442233849 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.13101548288086 bayes_pls_golite062009
  • protein transporter activity
    		•  1.09007120264887 bayes_pls_golite062009
  • SNARE binding
    		•  0.71459772253941 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.643064875848901 bayes_pls_golite062009
  • gated channel activity
    		•  0.621670335227137 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.370484918396857 bayes_pls_golite062009
  • channel activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.0435980899803177 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0172309833091902 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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