Protein Overview: CG13473-PA

General Information:
Name(s) found:	CG13473-PA / FBpp0075439 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7294366\|gb\|AAF49714.1\| CG13473 [Drosophila melanogaster] [NCBI NR] gi\|66772257\|gb\|AAY55440.1\| IP04051p [Drosophila melanogaster] [NCBI NR] gi\|66772187\|gb\|AAY55405.1\| IP04151p [Drosophila melanogaster] [NCBI NR] gi\|24664269\|ref\|NP_648717.1\| CG13473 [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG13473 (CG13473, FBgn0036442). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14721860..14722443. It has the cytological map location 70F3. Based on sequence similarity, it is predicted to have molecular function</span>: disulfide oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cell redox homeostasis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG13473-PA translation from_gene[CG13473 CG13473 FBgn0036442] seq_release:3 mol_weight=15527 cds_boundaries:(3L:14,677,720..14,678,136[+]) aa_length:139 transcript_info:[CG13473-RA seq_release:3] gene_info:[gene symbol:CG13473 FBgn0036442 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta] (Q9VUG9) CG13473 protein [DrosMelano7227.FASTAC.txt] (AE003533) CG13473 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG13473-PA [Drosophila melanogaster]gi\|24664269\|ref\|NP_648717.1\| CG13473-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:14721940..14722359; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714; MD5=f646d256bee7b5950a575417 [fly-100309-contam.fasta] IP04051p [Drosophila melanogaster] [nr-271106-contam.fasta] CG13473-PA [Drosophila melanogaster] [nr-271106-contam.fasta] IP04151p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:14721940..14722359; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714; MD5=f646d256bee7b5950a5754178cb7e5e8; length=139; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:14721940..14722359; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714; MD5=f646d256bee7b5950a5754178cb7e5e8; length=139; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Thioredoxin OS=Drosophila melanogaster GN=CG13473 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:14721940..14722359; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714,FlyMine:FBpp0075439,modMine:FBpp0075439; MD5=f646d256bee7b5950a5754178cb7e5e8; length=139; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:14728840..14729259; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714,FlyMine:FBpp0075439,modMine:FBpp0075439; MD5=f646d256bee7b5950a5754178cb7e5e8; length=139; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:14728840..14729259; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714,FlyMine:FBpp0075439,modMine:FBpp0075439; MD5=f646d256bee7b5950a5754178cb7e5e8; length=139; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] IP04051p OS=Drosophila melanogaster GN=CG13473 PE=2 SV=1 [DROME.fasta.20160308] FBpp0075439 type=protein; loc=3L:14728840..14729259; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714,FlyMine:FBpp0075439,modMine:FBpp0075439; MD5=f646d256bee7b5950a5754178cb7e5e8; length=139; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:14728840..14729259; ID=FBpp0075439; name=CG13473-PA; parent=FBgn0036442,FBtr0075689; dbxref=FlyBase:FBpp0075439,FlyBase_Annotation_IDs:CG13473-PA,GB_protein:AAF49714.1,REFSEQ:NP_648717,GB_protein:AAF49714,UniProt/TrEMBL:Q9VUG9,FlyMine:FBpp0075439,modMine:FBpp0075439; MD5=f646d256bee7b5950a5754178cb7e5e8; length=139; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	139 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	cell redox homeostasis [IEA]
Molecular Function:	disulfide oxidoreductase activity [ISS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MAAMQKKVII VDSKSYFDKL IDDAGTNKYV LVEFFATWCG PCAMIGPRLE QLASDYFGRM 60 61 LVLKIDVDEN EDLAVQYEVN SMPTFLIIKN RVTLIQFVGG NVERVVSTVE KFVGKVEDSK 120 121 EHKSKEGGAS SATVPKLER

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..139]	PSI-BLAST	29.154902	T7 DNA Polymerase Complexed To DNA Primer/Template and ddATP

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
antioxidant activity	3.8464796631544	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
protein disulfide isomerase activity	2.3913606099687	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.3913606099687	bayes_pls_golite062009
protein-disulfide reductase activity	2.24066563461479	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.23310780102446	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.18667085747706	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
transcription regulator activity	0.96297634785608	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
hydrolase activity	0.620302638089385	bayes_pls_golite062009
protein disulfide oxidoreductase activity	0.44918717550973	bayes_pls_golite062009
glutathione binding	0.2456976890622	bayes_pls_golite062009
transferase activity	0.245320538630117	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

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