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Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein-disulfide reductase activity
Acc: GO:0047134
Aspect: Molecular Function
Desc: Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
Synonyms:
  • NAD(P)H2:protein-disulfide oxidoreductase activity
  • insulin-glutathione transhydrogenase activity
  • protein-disulphide reductase activity
  • protein-dithiol:NAD(P)+ oxidoreductase activity
  • protein disulfide reductase activity
  • NAD(P)H:protein-disulfide oxidoreductase activity
  • protein-disulfide reductase (NAD(P)H) activity
  • disulfide reductase activity
  • protein disulphide reductase activity
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047134 - protein-disulfide reductase activity (interactive image map)
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