YRC Public Data Repository - Protein Structure Prediction

Protein:	CG13473-PA
Organism:	Drosophila melanogaster
Length:	139 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG13473-PA.

Description	E-value	Query Range	Subject Range
gi\|52006025, gi\|... - gi\|74316537\|ref\|YP_314277.1\| thioredoxin [Thiobacillus denitrificans ATCC 25259], gi\|74056032\|gb\|AAZ...	135.0	[0..6]	[126..2]
gi\|121608517, gi... - gi\|121608517\|ref\|YP_996324.1\| thioredoxin [Verminephrobacter eiseniae EF01-2], gi\|121553157\|gb\|ABM57...	134.0	[0..10]	[136..2]
gi\|56461094, gi\|... - gi\|56461094\|ref\|YP_156375.1\| thioredoxin domain-containing protein [Idiomarina loihiensis L2TR], gi\|...	134.0	[0..4]	[135..1]
gi\|116057647 - gi\|116057647\|emb\|CAL53850.1\| Thioredoxin (ISS) [Ostreococcus tauri]	134.0	[0..5]	[113..109]
gi\|107103574 - gi\|107103574\|ref\|ZP_01367492.1\| hypothetical protein PaerPA_01004644 [Pseudomonas aeruginosa PACS2]	134.0	[0..7]	[134..5]
gi\|84319139, gi\|... - gi\|84319139\|ref\|ZP_00967542.1\| COG3118: Thioredoxin domain-containing protein [Pseudomonas aeruginos...	134.0	[0..7]	[129..5]
gi\|115587318, gi... - gi\|32039231\|ref\|ZP_00137503.1\| COG3118: Thioredoxin domain-containing protein [Pseudomonas aeruginos...	133.0	[0..7]	[134..5]
gi\|110593092, gi... - gi\|110593092\|ref\|ZP_01381446.1\| thioredoxin [Acidovorax sp. JS42], gi\|110337599\|gb\|EAT57311.1\| thior...	133.0	[0..3]	[113..21]
gi\|15599256, gi\|... - gi\|9950258\|gb\|AAG07448.1\|AE004822_8 probable thioredoxin [Pseudomonas aeruginosa PAO1], gi\|15599256\|... gi\|84325193, gi\|... - gi\|84325193\|ref\|ZP_00973233.1\| COG3118: Thioredoxin domain-containing protein [Pseudomonas aeruginos... gi\|218769882, gi... - gi\|218889659\|ref\|YP_002438523.1\| putative thioredoxin [Pseudomonas aeruginosa LESB58], gi\|218769882\|... gi\|11351923 - pir\|\|E83138 probable thioredoxin PA4061 [imported] - Pseudomonas aeruginosa (strain PAO1)	133.0	[0..7]	[134..5]
gi\|152987483, gi... - gi\|94417004\|ref\|ZP_01296826.1\| hypothetical protein PaerP_01001200 [Pseudomonas aeruginosa PA7], gi\|...	133.0	[0..7]	[134..5]

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Predicted Domain #1

Region A:
Residues: [1-139]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAMQKKVII VDSKSYFDKL IDDAGTNKYV LVEFFATWCG PCAMIGPRLE QLASDYFGRM  60
   61 LVLKIDVDEN EDLAVQYEVN SMPTFLIIKN RVTLIQFVGG NVERVVSTVE KFVGKVEDSK 120
  121 EHKSKEGGAS SATVPKLER

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.154902
Match:	1skrB
Description:	T7 DNA Polymerase Complexed To DNA Primer/Template and ddATP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.8464796631544	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
protein disulfide isomerase activity	2.3913606099687	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.3913606099687	bayes_pls_golite062009
protein-disulfide reductase activity	2.24066563461479	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.23310780102446	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.18667085747706	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
transcription regulator activity	0.96297634785608	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
hydrolase activity	0.620302638089385	bayes_pls_golite062009
protein disulfide oxidoreductase activity	0.44918717550973	bayes_pls_golite062009
glutathione binding	0.2456976890622	bayes_pls_golite062009
transferase activity	0.245320538630117	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: