Protein Overview: btl-PA, btl-PB

General Information:
Name(s) found:	btl-PB / FBpp0100143 [FlyBase] btl-PA / FBpp0075520 [FlyBase]
Description(s) found: Found 31 descriptions. SHOW ALL	The gene breathless is referred to in FlyBase by the symbol Dmel\btl (CG32134, FBgn0005592). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14068872..14075985. It has the cytological map location 70D2. Based on sequence similarity, it is predicted to have molecular function</span>: fibroblast growth factor receptor activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; open tracheal system development; organ morphogenesis; organ development; cellular component movement; regulation of neurogenesis; microspike assembly; epithelial cell type specification, open tracheal system; cell motility; genital disc development; cell projection organization; tube morphogenesis; regulation of neuron projection development. 51 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system; embryonic/larval tracheal system; portion of tissue; primordium; tracheal system; embryonic/larval dorsal branch; cell part; embryonic glial cell; embryonic dorsal branch; embryonic/larval visceral branch; embryonic dorsal trunk; embryonic tracheal system; cell projection; embryonic ganglionic branch; embryonic trachea. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene breathless is referred to in FlyBase by the symbol Dmel\btl (CG32134, FBgn0005592). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14068872..14075985. It has the cytological map location 70D2. Based on sequence similarity, it is predicted to have molecular function</span>: fibroblast growth factor receptor activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; open tracheal system development; organ morphogenesis; organ development; cellular component movement; regulation of neurogenesis; microspike assembly; epithelial cell type specification, open tracheal system; cell motility; genital disc development; cell projection organization; tube morphogenesis; regulation of neuron projection development. 51 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system; embryonic/larval tracheal system; portion of tissue; primordium; tracheal system; embryonic/larval dorsal branch; cell part; embryonic glial cell; embryonic dorsal branch; embryonic/larval visceral branch; embryonic dorsal trunk; embryonic tracheal system; cell projection; embryonic ganglionic branch; embryonic trachea. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1052 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [IC][ISS][NAS]
Biological Process:	endoderm development [NAS] epithelial cell type specification, open tracheal system [IMP] mesoderm development [NAS] fibroblast growth factor receptor signaling pathway [NAS][TAS] terminal branching, open tracheal system [IMP][TAS] protein amino acid phosphorylation [IEA][NAS] tracheal outgrowth, open tracheal system [IMP] filopodium assembly [IMP] open tracheal system development [IEP][NAS][TAS] glial cell migration [IMP] salivary gland morphogenesis [NAS] secondary branching, open tracheal system [IMP][TAS] muscle organ development [NAS] morphogenesis of a branching structure [TAS] epithelial cell migration, open tracheal system [IMP][TAS] primary branching, open tracheal system [IMP][TAS] central nervous system development [NAS] negative regulation of axon extension [IMP] genital disc development [IEP]
Molecular Function:	fibroblast growth factor receptor activity [ISS][TAS] ATP binding [IEA] protein tyrosine kinase activity [NAS] protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVPITLVM IIAIVSAAAD LGCDYGHHRC YIDVTVENSP RQRHLLSDMD ITLQCVRPMA  60
   61 KWFYEDKFQL RATLLRLERA QSGNSGNYGC LDSQNRWYNI SLVVGHKEPV GNDIASFVKL 120
  121 EDAPALPESD LFFQPLNESR SLKLLQPLPK TVQRTAGGLF QLNCSPMDPD AKGVNISWLH 180
  181 NDTQILGGRG RIKLKRWSLT VGQLQPEDAG SYHCELCVEQ DCQRSNPTQL EVISRKHTVP 240
  241 MLKPGYPRNT SIALGDNVSI ECLLEDSALE PKITWLHKGN ADNIDDLLQR LREQSQLPVD 300
  301 VTRLITRMDE PQVLRLGNVL MEDGGWYICI AENQVGRTVA ASYVDLYSPS DTTTVRTTTT 360
  361 TTVASPIPTA STGEDNDDDV ENPAAEASGG VGPPVFRKEL KRLQHSLSGN TVNLACPVYG 420
  421 KANITWTKDK KPLNRELGVY VQKNWTLRFV EATSEDSGLY NCKVCNAWGC IQFDFSVQIN 480
  481 DRTRSAPIIV VPQNQTVKVN GSLVMKCTVY SDLHPTVSWK RVVLKNASLD GLKSVEIQNL 540
  541 NFTVTNDSVV LTLRNVTFDQ EGWYTCLASS GLGRSNSSVY LRVVSPLPPL EIYALLHAHP 600
  601 LGFTLAAITI VALFLLGSAF ITFMLRRLRR EKLLKLRIET VHQWTKKVII YRPGGEEGSG 660
  661 CSSGDLQMPV IRIEKQRTTV STTGTGGTDP AQGFNEYEFP LDSNWEIPRQ QLSLGSILGE 720
  721 GAFGRVVMAE AEGLPRSPQL AETIVAVKMV KEEHTDTDMA SLVREMEVMK MIGKHINIIN 780
  781 LLGCCSQGGP LWVIVEYAPH GNLKDFLKQN RPGAPQRRSD SDGYLDDKPL ISTQHLGEKE 840
  841 LTKFAFQIAR GMEYLASRRC IHRDLAARNV LVSDGYVMKI ADFGLARDIQ DTEYYRKNTN 900
  901 GRLPIKWMAP ESLQEKKYDS QSDVWSYGVL LWEIMTYGDQ PYPHILSAEE LYSYLITGQR 960
  961 MEKPAKCSLN IYVVMRQCWH FESCARPTFA ELVESFDGIL QQASSNPNDA YLDLSMPMLE1020
 1021 TPPSSGDEDD GSDTETFRET SPLRYQYTYK FN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: btl-PA, btl-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: