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Protein Overview: aay-PA

General Information:
Name(s) found: aay-PA / FBpp0076185 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene astray is referred to in FlyBase by the symbol Dmel\aay (CG3705, FBgn0023129). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9416353..9417904. It has the cytological map location 67B5. Based on sequence similarity, it is predicted to have molecular function</span>: phosphoserine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: axon guidance. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 270 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: L-serine biosynthetic process [IEA][NAS]
    axon guidance [IMP]
    peripheral nervous system development [TAS]
    Molecular Function: phosphoserine phosphatase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSVLSLAR PAAATNGHNL LTKQLNCNGN GTTGGAAKTT VASAITPPKQ PQLAAKVIQQ  60
   61 SQIVCFDVDS TVICEEGIDE LAEYCGKGSE VARVTKEAMG GAMTFQDALK IRLNIIRPTQ 120
  121 QQVRDFIQER PSTLSKNVKR FVSHLKAEGK QVYLISGGFD CLIAPVANEL GIPLKNVYAN 180
  181 KMLFDYLGEY DSFDINQPTS RSGGKAEAIA LIRKENSDDS LITMIGDGAT DLEAVPPANY 240
  241 FIGFGGNVVR PEVYRRAQYY VTDFEQLMGQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..270] PSI-BLAST 21.09691 Phosphoserine phosphatase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoserine phosphatase activity
    		•  2.609399110972 bayes_pls_golite062009
  • hydrolase activity
    		•  1.64652153606264 bayes_pls_golite062009
  • catalytic activity
    		•  1.55296860681783 bayes_pls_golite062009
  • transporter activity
    		•  1.14896368703744 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.05797491861618 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.993187180025513 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.927418188183455 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.90274219445561 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.877641462417465 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  0.851191468282636 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  0.787963367346595 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.579515117605331 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.53313021679328 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.506075412583888 bayes_pls_golite062009
  • calcium ion transmembrane transporter activity
    		•  0.493750063720989 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.478053552351263 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.457373743206143 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.436378691321164 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.435443892463434 bayes_pls_golite062009
  • ATPase activity
    		•  0.430637728534119 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.403861776663831 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.402056642959593 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.375649206782765 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.375649206782765 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.374004042755094 bayes_pls_golite062009
  • binding
    		•  0.309823128403058 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.273204868537985 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.204834938376666 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.117331448391929 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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