Protein Overview: FBpp0300668, PGR...

General Information:
Name(s) found:	FBpp0300668 [FlyBase] PGRP-LC-PB / FBpp0088492 [FlyBase]
Description(s) found: Found 32 descriptions. SHOW ALL	type=protein; loc=3L:join(9335428..9336229,9338000..9338224,9340740..9341275); ID=FBpp0300668; name=PGRP-LC-PH; parent=FBgn0035976,FBtr0308349; dbxref=FlyBase:FBpp0300668,FlyBase_Annotation_IDs:CG4432-PH,REFSEQ:NP_001246693,GB_protein:AFH04364; MD5=ed39a7ef7654d617b5a1abb16c401e37; length=520; release=r5.56; species=Dmel; [FlyBase] The gene Peptidoglycan recognition protein LC is referred to in FlyBase by the symbol Dmel\PGRP-LC (CG4432, FBgn0035976). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9331910..9341436. It has the cytological map location 67B1. There is experimental evidence that it has the molecular function</span>: Gram-negative bacterial binding; peptidoglycan binding. There is experimental evidence that it is involved in the biological process</span>: immune response; response to bacterium; defense response to Gram-negative bacterium; positive regulation of antibacterial peptide biosynthetic process; antimicrobial humoral response; antibacterial humoral response. 36 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	520 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [NAS] integral to membrane [ISS][NAS][TAS]
Biological Process:	response to bacterium [IMP] immune response [IMP][ISS] defense response to Gram-negative bacterium [IMP][TAS] peptidoglycan catabolic process [IEA] innate immune response [NAS][TAS] phagocytosis [TAS] detection of bacterium [NAS] antibacterial humoral response [IDA] antimicrobial humoral response [IMP] defense response [NAS] positive regulation of antibacterial peptide biosynthetic process [IMP][TAS] positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [NAS]
Molecular Function:	peptidoglycan receptor activity [NAS][TAS] peptidoglycan binding [IDA][ISS][NAS][TAS] pattern recognition receptor activity [TAS] protein binding [IEA] protein dimerization activity [NAS] Gram-negative bacterial cell surface binding [IDA] N-acetylmuramoyl-L-alanine amidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFSNETEMS QCSNAKRRVN DPLTGPKNCS TSSTDSGVIL NDNVAAFRPE KETKDRGTGE  60
   61 GQFQSKSEEK TESKRISVEH TVNITTENVG KTSSPAVSIR STTISVVSID DNAIDSSSID 120
  121 SDSEAEAEDY TVQKLGHQVT YPPNSSHLRD LNQGLTVISR HVAPGEAAVP PPNPLEAGIV 180
  181 AKQILNGNLA VATPTSPAGG ATQGIGSIAL TNSTDVTFGD KHFYEGPVTI QQFLIDNRDK 240
  241 WKPGEGPAGG QDNPAFNGGP STNGSAPGSK HEDPAQTPPI CPFLPNTVGR KAVTVTVVFV 300
  301 TLTFLLGIVL ATTTNLFGKT LNQSKIRDDD DYRQNIPINS TIDLDNIGGG LILRFVERQQ 360
  361 WLAQPPQKEI PDLELPVGLV IALPTNSENC STQAICVLRV RLLQTYDIES SQKCDIAYNF 420
  421 LIGGDGNVYV GRGWNKMGAH MNNINYDSQS LSFAYIGSFK TIQPSAKQLS VTRLLLERGV 480
  481 KLGKIAPSYR FTASSKLMPS VTDFKADALY ASFANWTHWS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.23

Protein Overview: FBpp0300668, PGR...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: