Protein Overview: RecQ4-PA

General Information:
Name(s) found:	RecQ4-PA / FBpp0076452 [FlyBase]
Description(s) found: Found 20 descriptions. SHOW ALL	The gene RecQ4 is referred to in FlyBase by the symbol Dmel\RecQ4 (CG7487, FBgn0040290). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8163919..8168998. It has the cytological map location 66B10. Based on sequence similarity, it is predicted to have molecular function</span>: DNA helicase activity; DNA-dependent ATPase activity; helicase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell proliferation; positive regulation of G2/M transition of mitotic cell cycle; double-strand break repair; positive regulation of DNA replication; base-excision repair; oogenesis. 17 alleles are reported. The phenotype of these alleles is annotated with: chorion. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1579 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	cell division [IMP] DNA repair [ISS] eggshell chorion gene amplification [IMP] base-excision repair [IMP] oogenesis [IMP] DNA replication [IMP][ISS] positive regulation of cell proliferation [IMP] DNA recombination [IEA] positive regulation of DNA replication [IMP] larval development [IMP] positive regulation of G2/M transition of mitotic cell cycle [IMP] double-strand break repair [IMP]
Molecular Function:	nucleic acid binding [IEA] ATP binding [IEA] DNA helicase activity [ISS] zinc ion binding [IEA] DNA-dependent ATPase activity [ISS] ATP-dependent helicase activity [IEA] helicase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDSVFKLKY QKYKLRVKVW EKDFKKKNGR VPSKYDIRDA SQEIRDSYKM YYKLKTSFLE  60
   61 ETLNDVLSED GYDILEMSQA SDFGVSMLDQ DVSLNEGPQL PLDISALVGP QSSGNLEEIP 120
  121 QSVEGSFSNL IDLPNRQVLT NLVNRDENHV IRKFEAVEEL PINQNAWGLN VSKKPPAPPQ 180
  181 PVEASKSAPG HGKQPKAGAS LKPSLSAKLF QSSRGFAKRN PRKPLSRCVS SSSSTTSLSS 240
  241 VPTDHHEELL DFETILIRKA QEYKEKQQAI ANNPMLASEH SKESIKTLVD DGWLRRNTKE 300
  301 NTLDEEVPFA EANNNSGTSK KTNFGLANLD LSKLKPTVKE EKVLQAKPDQ MAIIQELQTD 360
  361 MNSSMNQKPD HLNHTPPASS QKSVAPKNKP PPSEQETDSD SDSVVAESEE EQEPQEYRQL 420
  421 SKRRKIVSTA SGKVEVAAPV EIPNKVEPET ETFAQENPDF SADEDQDATY VPENKKKDKA 480
  481 KRKQAAGKQK TTKPKAEPKP KTEKKAKVKA EKKPKAEKKP RNSKKAIAVE PAPDPEEDER 540
  541 QPLNPEDLKY VLALEAGDIT SVPRINVQDL EEADATAQRY IRTFAAGPNP GLSEGSNIRV 600
  601 DEKRAAARKK LEERIAAGKL NENFVTINIQ KKKFVRGKKS VNFSKYKKQQ WRHKKRVAAL 660
  661 SGPDMDMGGC DGGVLTCFQC GGVGHFAQQC KVKGDSLLPL SAQLEEDPSP FPTLAEAQEM 720
  721 ASQGAVVAHS RNISRLPQAA NAAILQGDEL NESEEDDQES SGDEEVQQHP DPNWSSDEMD 780
  781 VDFEALDAAV EASLSQPVSQ EKAASPIKTY VGHKIPEEFL KQAGLDTTAS SSNRSQHGGV 840
  841 KPLYDLLPDG SVQDTTPEVL EALHMFGHTN FRKGQDRAIM RTLSGLSSLV TLSTGSGKSL 900
  901 CYQLPAYLYS RKVGAITLVI SPLVSLMEDQ VTGVPHFLRA HCLHTNQTAP QRMKIQQMIA 960
  961 NGEIDILLVS PEAVVAGERA TGFGAILRQL PPIAFACIDE AHCVSQWSHN FRPSYLMICK1020
 1021 VLRKNLGVRT VLGLTATATL PTRVSIINHL GISDGERGII SDIPLPDNLV LSVSKDENRD1080
 1081 AALLQLLNSE RFEPCQSIII YCTRRDECER IAGFIRTCVQ DRREPTQDQT KKRKRVNWQA1140
 1141 EPYHAGMPAS RRRTVQKAFM SNELRIVVAT IAFGMGINKP DIRAVIHYNM PRNFESYVQE1200
 1201 IGRAGRDGLP SHCHLFLDAK GGDQSELRRH VYSNSIDRHV IRKLLQKIFV PCSCDKEASK1260
 1261 RTALPIPLEG DGPRVHMCPG HEIGFSVEKT VEMLDIPAEN ISTLLCYMEL DPRWCISVLS1320
 1321 SAYVMAKVIS YGGPKYLKHA AKECPPLAMA IALQIRDKTF KEDSNIIEFS VTDIAAGIGW1380
 1381 NSGVVKYQLK DLEWVKVNGY PKRSPITVSF YDLGFRIKVP GDFTESEIDN ALDTLYTRSV1440
 1441 KQERTQLIQL QYVAHGLAAV AYSSCGQCCN ADFPQDRGEQ LKAIVRNYFA NDYPQDLELE1500
 1501 IEPSNVPDEN IIDDVHALIN MYPDNTFTGR NIARIFHGIM SPNYPAVIWG RCKFWRAHVK1560
 1561 VDFNRILHLA NMAIIKRRT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: RecQ4-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: