YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: G-ialpha65A-PA

General Information:
Name(s) found: G-ialpha65A-PA / FBpp0076643 [FlyBase]
Description(s) found:
SHOW ONLY BEST
  • gi|7295305|gb|AAF50626.1| G protein alphai subunit 65A [Drosophila melanogaster] [NCBI NR]
  • gi|17137790|ref|NP_477502.1| G protein alphai subunit 65A [Drosophila melanogaster] [NCBI NR]
  • gi|15291651|gb|AAK93094.1| LD22201p [Drosophila melanogaster] [NCBI NR]
  • gi|14286126|sp|P20353.2|GNAI_DROME RecName: Full=Guanine nucleotide-binding protein G(i) subunit alpha 65A [NCBI NR]
  • G protein alpha i subunit OS=Drosophila melanogaster GN=Galphai PE=1 SV=2 [Swiss-Prot]
  • (P20353) Guanine nucleotide-binding protein G(i), alpha subunit 65A [Swiss-Prot]
  • The gene G protein Ã?&#142;Ã?±i subunit 65A is referred to in FlyBase by the symbol Dmel\G-iÃ?&#142;Ã?±65A (CG10060, FBgn0001104). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:6965844..6973153. It has the cytological map location 65D5. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: asymmetric protein localization involved in cell fate determination; asymmetric neuroblast division; establishment of spindle orientation; establishment of glial blood-brain barrier; cortical actin cytoskeleton organization; septate junction assembly; regulation of protein localization; asymmetric cell division; ventral cord development. 28 alleles are reported. The phenotypes of these alleles are annotated with: RP2 neuron; neuroblast; embryonic neuroblast; chaeta; medial triple row; RP2sib neuron; EL neuron. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG10060-PA translation from_gene[CG10060 G-ialpha65A FBgn0001104] seq_release:3 mol_weight=40596 cds_boundaries:(3L:6,932,875..6,939,167[-]) aa_length:355 transcript_info:[CG10060-RA seq_release:3] gene_info:[gene symbol:G-ialpha65A FBgn0001104 gene_b [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003560) G-oalpha65A gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG10060-PA [Drosophila melanogaster]gi|15291651|gb|AAK93094.1| LD22201p [Drosophila melanogaster]gi|17137790|ref|NP_477502.1| CG10060-PA [Drosophila melanogaster]gi|14286126|sp|P20353|GBI5_DROME Guanine nucleotide-binding protein G(i), alpha subunit 65 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(6966443..6966633,6966690..6966878,6966938..6967032,6967102..6967573,6972618..6972738); ID=FBpp0076643; name=G-ialpha65A-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_pro [fly-100309-contam.fasta]
  • G protein alphai subunit 65A CG10060-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Guanine nucleotide-binding protein G(i) subunit alpha 65A [nr-271106-contam.fasta]
  • LD22201p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG10060-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:complement(6966443..6966633,6966690..6966878,6966938..6967032,6967102..6967573,6972618..6972738); ID=FBpp0076643; name=G-ialpha65A-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_protein:AAF50626.1,REFSEQ:NP_477502,GB_protein:AAF50626; MD5=2b71ed52268d723ca2114a08a67481e2; length=355; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(6966443..6966633,6966690..6966878,6966938..6967032,6967102..6967573,6972618..6972738); ID=FBpp0076643; name=G-ialpha65A-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_protein:AAF50626.1,REFSEQ:NP_477502,GB_protein:AAF50626; MD5=2b71ed52268d723ca2114a08a67481e2; length=355; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Guanine nucleotide-binding protein G(i) subunit alpha 65A OS=Drosophila melanogaster GN=G-ialpha65A PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:complement(6966443..6966633,6966690..6966878,6966938..6967032,6967102..6967573,6972618..6972738); ID=FBpp0076643; name=G-ialpha65A-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_protein:AAF50626.1,REFSEQ:NP_477502,GB_protein:AAF50626,FlyMine:FBpp0076643,modMine:FBpp0076643; MD5=2b71ed52268d723ca2114a08a67481e2; length=355; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:complement(join(6979518..6979638,6974002..6974473,6973838..6973932,6973590..6973778,6973343..6973533)); ID=FBpp0076643; name=Galphai-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_protein:AAF50626.1,REFSEQ:NP_477502,GB_protein:AAF50626,FlyMine:FBpp0076643,modMine:FBpp0076643; MD5=2b71ed52268d723ca2114a08a67481e2; length=355; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(join(6979518..6979638,6974002..6974473,6973838..6973932,6973590..6973778,6973343..6973533)); ID=FBpp0076643; name=Galphai-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_protein:AAF50626.1,REFSEQ:NP_477502,GB_protein:AAF50626,FlyMine:FBpp0076643,modMine:FBpp0076643; MD5=2b71ed52268d723ca2114a08a67481e2; length=355; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0076643 type=protein; loc=3L:complement(join(6979518..6979638,6974002..6974473,6973838..6973932,6973590..6973778,6973343..6973533)); ID=FBpp0076643; name=Galphai-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_protein:AAF50626.1,REFSEQ:NP_477502,GB_protein:AAF50626,FlyMine:FBpp0076643,modMine:FBpp0076643; MD5=2b71ed52268d723ca2114a08a67481e2; length=355; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:complement(join(6979518..6979638,6974002..6974473,6973838..6973932,6973590..6973778,6973343..6973533)); ID=FBpp0076643; name=Galphai-PA; parent=FBgn0001104,FBtr0076934; dbxref=FlyBase:FBpp0076643,FlyBase_Annotation_IDs:CG10060-PA,GB_protein:AAF50626.1,REFSEQ:NP_477502,GB_protein:AAF50626,UniProt/Swiss-Prot:P20353,FlyMine:FBpp0076643,modMine:FBpp0076643; MD5=2b71ed52268d723ca2114a08a67481e2; length=355; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 355 amino acids

    Gene Ontology:
    Cellular Component: heterotrimeric G-protein complex [ISS][NAS]
    cell cortex [TAS]
    apical cortex [IDA]
    Biological Process: cortical actin cytoskeleton organization [IMP]
    ventral cord development [IMP]
    G-protein coupled receptor protein signaling pathway [ISS][NAS]
    establishment of mitotic spindle localization [TAS]
    asymmetric protein localization involved in cell fate determination [IMP]
    regulation of protein localization [IMP]
    septate junction assembly [IMP]
    establishment of spindle orientation [IMP]
    asymmetric cell division [IMP]
    asymmetric neuroblast division [IMP]
    establishment of glial blood-brain barrier [IMP]
    Molecular Function: GTP binding [IEA]
    protein binding [IPI][NAS]
    GTPase activity [ISS][NAS]
    signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCAVSTARD KEAIERSKNI DRALRAEGER AASEVKLLLL GAGESGKSTI VKQMKIIHDT  60
   61 GYSQEECEEY RRVVFSNTVQ SLMVIIRAMG RLKIEFADPS RTDIARQFFT HASAADEGIL 120
  121 LPEIVLLMKK LWADGGVQQS FARSREYQLN DSAGYYLNSL DRIAQPNYIP TQQDVLRTRV 180
  181 KTTGIIETHF SCKQLHFKLF DVGGQRSERK KWIHCFEGVT AIIFCVALSG YDLVLAEDEE 240
  241 MNRMIESLKL FDSICNSKWF VETSIILFLN KKDLFEEKIK RSPLTICFPE YTGTNTFEEA 300
  301 ANYIRMKFEN LNKRKDQKEI YTHLTCATDT NNVKFVFDAV TDVIIKNNLK QIGLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle