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The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. The process whereby a relatively unspecialized cell acquires the specialized features of a glial cell. The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: establishment of glial blood-brain barrier
Acc: GO:0060857
Aspect: Biological Process
Desc: Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
Proteins in PDR annotated with:
   This term: 29 [Search]
   Term or descendants: 29 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060857 - establishment of glial blood-brain barrier (interactive image map)
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