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Protein Overview: ago-PA, ago-PC, ...

General Information:
Name(s) found: ago-PA / FBpp0073103 [FlyBase]
ago-PB / FBpp0073102 [FlyBase]
ago-PC / FBpp0073101 [FlyBase]
Description(s) found:
Found 53 descriptions.
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  • The gene archipelago is referred to in FlyBase by the symbol Dmel\ago (CG15010, FBgn0041171). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4246326..4254309. It has the cytological map location 64A11-64A12. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; regulation of mitosis; DNA endoreduplication. 38 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene archipelago is referred to in FlyBase by the symbol Dmel\ago (CG15010, FBgn0041171). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4246326..4254309. It has the cytological map location 64A11-64A12. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; regulation of mitosis; DNA endoreduplication. 38 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene archipelago is referred to in FlyBase by the symbol Dmel\ago (CG15010, FBgn0041171). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4246326..4254309. It has the cytological map location 64A11-64A12. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; regulation of mitosis; DNA endoreduplication. 38 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1326 amino acids

    Gene Ontology:
    Cellular Component: SCF ubiquitin ligase complex [NAS]
    Biological Process: negative regulation of growth [IMP]
    regulation of mitosis [IMP]
    cyclin catabolic process [TAS]
    regulation of exit from mitosis [TAS]
    regulation of proteolysis [TAS]
    DNA endoreduplication [IMP]
    Molecular Function: ubiquitin-protein ligase activity [ISS]
    cyclin binding [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERGCPAASS ESVTSAGERT QSAVTSSTST WVKSQASTSR KTEASEESGL GAVDAEVGAG  60
   61 REAFVSMSTL REDVEDVCVS SNSQHGFAVV LDDESSTFEI SSSNSLPTSA GAASTVGVVA 120
  121 VDDSSSTDTL NGGHPDLGHP ASSEHSRQGF FNEDNEDPPV VCLINDDDDD EEPEPEEDDE 180
  181 EELIEDEDED AVDIVTGAIS CPNTSQLALA DGTIMAADGS KIFLETPVVE EAQPHPGQVV 240
  241 TTGSQSELTG KPKRLSDEFL LGEEDQAENL ALGRCIKSEP VNPVDDNPSE GDDGATCFSL 300
  301 HDRLMSVRLK QMSLTANTVS NPSPAASANA AAPEEASTSN SSSTSSSALS RADIESMDLI 360
  361 ERRDFETEQR LTGGIILRTS SMVSQNKLNL SLIKSMAGGS KAANGSGTAN SDDWPSSSNG 420
  421 RTVSSDSKYT YKDLSTTPTS SRKYTNSRLS KSTAKLNLGS SLGASSCSQH RSGSSSTSKS 480
  481 MESSTSCTGA ARTDVYTNTN SNDYPSLAPT TSGSSTSGGS CQQDQEENVS ASVSYSSVGS 540
  541 QTSQESGCSR TTAINPTAAC STGSACLGDS QASTSASTSS GAGASNRCQY ATTSTTKAAR 600
  601 QVNASAQTQE RFLTRSNPPA ASGAGSVGAN PTASVRQRRN GSSDVVHLEV VVEEGAGGGD 660
  661 GGVVEPGDFS AEEPWANCDE ENNCSDLEEI CTCQNGNGSS YGGSNASLSE TFDMDAMDPD 720
  721 EPISLSLSSA SAGFTEYSLT NPSSLMSHQR KRKFNEGRLL DGGDYSVTIS SSGEVGGPGS 780
  781 GVSDNCRKRI AYDFASTPRS SQHLGPTAVL SVTPSSHLTS STPGSALGRR TPRSVPSRDN 840
  841 PPPELQHWLA QFQRWSHVER LLALDRLIDH CDPSQVRHMM KVIEPQFQRD FISLLPRELA 900
  901 LFVLSYLEPK DLLRAAQTCR SWRFLCDDNL LWKEKCRKAQ ILAEPRSDRP KRGRDGNMPP 960
  961 IASPWKAAYM RQHIIEMNWR SRPVRKPKVL KGHDDHVITC LQFSGNRIVS GSDDNTLKVW1020
 1021 SAVNGKCLRT LVGHTGGVWS SQMSGNIIIS GSTDRTLKVW DMDSGACVHT LQGHTSTVRC1080
 1081 MHLHGSKVVS GSRDATLRVW DIEQGSCLHV LVGHLAAVRC VQYDGKLIVS GAYDYMVKIW1140
 1141 HPERQECLHT LQGHTNRVYS LQFDGLHVVS GSLDTSIRVW DVETGNCKHT LMGHQSLTSG1200
 1201 MELRQNILVS GNADSTVKVW DITTGQCLQT LSGPNKHHSA VTCLQFNSRF VVTSSDDGTV1260
 1261 KLWDVKTGDF IRNLVALDSG GSGGVVWRIR ANDTKLICAV GSRNGTEETK LMVLDFDVEG1320
 1321 ACVKCS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle