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Protein Overview: MAN1-PB, MAN1-PA...

General Information:
Name(s) found: FBpp0311863 [FlyBase]
MAN1-PB / FBpp0072076 [FlyBase]
MAN1-PA / FBpp0072075 [FlyBase]
Description(s) found:
Found 40 descriptions.
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  • type=protein; loc=2R:19922221..19924173; ID=FBpp0311863; name=MAN1-PC; parent=FBgn0034962,FBtr0345949; dbxref=FlyBase:FBpp0311863,FlyBase_Annotation_IDs:CG3167-PC; MD5=339326f1a6bffaa1f49fc6380bf3e992; length=650; release=r5.56; species=Dmel; [FlyBase]
  • The gene MAN1 is referred to in FlyBase by the symbol Dmel\MAN1 (CG3167, FBgn0034962). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19921732..19924231. It has the cytological map location 60B5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: RNA binding; nucleotide binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: mRNA processing. 11 alleles are reported. The phenotypes of these alleles are annotated with: posterior crossvein; ovary; testis; wing blade; wing; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene MAN1 is referred to in FlyBase by the symbol Dmel\MAN1 (CG3167, FBgn0034962). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19921732..19924231. It has the cytological map location 60B5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: RNA binding; nucleotide binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: mRNA processing. 11 alleles are reported. The phenotypes of these alleles are annotated with: posterior crossvein; ovary; testis; wing blade; wing; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 650 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IEA]
    Biological Process: mRNA processing [IEA]
    Molecular Function: nucleotide binding [IEA]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTESLNSLS DKELHRKLIQ SGFPSTPVTE TTRAVLIEKL RKHTRADKLK KRSNKYVLYS  60
   61 KEQQESPPFP QYHQYHAPQP PQNYANGLDN NNDLDQTGGS SAYNRSLDES DSSPLQLSAS 120
  121 KMYAPPPVVA SNYDGDCSPH SLGLNGKYLQ PCSMPYAIDT SNNYGKPSGK AKLSDGGVVN 180
  181 RLLSFRDTTI QRKFNYPTGQ ASRIPLRKER LTRFALSDLK SFIRNPDIRP YVIPRVLISL 240
  241 FLIFLTIITV LYVGKRFEQS PIDKAALKYT LCNPNDMQMI SEKVNCIEKD SLRGALDMSE 300
  301 ELFRHLNERA RLHHCKDANL SPALEIGEFV REMVSNPKTH RGNLHSNLMA AKYLITENPQ 360
  361 WSIQVVDSTK HLGQTSHFEL SEPNLPLKCI VLKKVTRFFT VIGALLLIVA GFLIVYVAVV 420
  421 IYRVKQKEAL LAVDQFQKDI INELIYLSSQ SESPEVVINQ LQEKFLPAKK RSKLLSSWNK 480
  481 ALKQLEKNDS RVLFGMVNRD GKAMRTIAWN RNVDKKDVGL VKKWQSPAFD NSNKIANPPT 540
  541 PCLKIRHMFD SSEVDQANLK QSIVESIIEK VGTRCKICDV QLDVQSCCVY IRCASEEDAG 600
  601 TIHKEINGWW FDKRLISIKF LRLERYLSRF PKPSAEPLYF HTNEAANTHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..59] PSI-BLAST 4.09691 Inner nuclear membrane protein emerin
    2 View Details [60..236] PSI-BLAST 5.0 Fibrinogen
    3 View Details [237..390] deduced N/A No confident structure predictions are available.
    4 View Details [391..526] PSI-BLAST 21.045757 No description for 2ch0A was found.
    5 View Details [527..650] PSI-BLAST 24.69897 No description for 2pe8A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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