Protein Overview: Phm-PB, Phm-PA

General Information:
Name(s) found:	Phm-PA / FBpp0072112 [FlyBase] Phm-PB / FBpp0072111 [FlyBase]
Description(s) found: Found 40 descriptions. SHOW ALL	The gene Peptidylglycine-Ă?Ă?Âą-hydroxylating monooxygenase is referred to in FlyBase by the symbol Dmel\Phm (CG3832, FBgn0019948). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19872750..19875990. It has the cytological map location 60A16. Based on sequence similarity, it is predicted to have molecular function</span>: peptidylglycine monooxygenase activity. It is reported to be involved in the biological process</span>: peptide amidation. 7 alleles are reported. The phenotypes of these alleles are annotated with: pupa; puparium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene Peptidylglycine-Ă?Ă?Âą-hydroxylating monooxygenase is referred to in FlyBase by the symbol Dmel\Phm (CG3832, FBgn0019948). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19872750..19875990. It has the cytological map location 60A16. Based on sequence similarity, it is predicted to have molecular function</span>: peptidylglycine monooxygenase activity. It is reported to be involved in the biological process</span>: peptide amidation. 7 alleles are reported. The phenotypes of these alleles are annotated with: pupa; puparium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	365 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA]
Biological Process:	peptide metabolic process [IEA] peptide amidation [NAS] oxidation reduction [IEA] catecholamine metabolic process [IEA] memory [IMP]
Molecular Function:	peptidylglycine monooxygenase activity [ISS][NAS] copper ion binding [IEA] dopamine beta-monooxygenase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRISEIAAS VGLLLLIGVI SVDGLVKEGD YQNSLYQQNL ESNSATGATA SFPFLMPNVS  60
   61 PQTPDLYLCT PIKVDPTTTY YIVGFNPNAT MNTAHHMLLY GCGEPGTSKT TWNCGEMNRA 120
  121 SQEESASPCG PHSNSQIVYA WARDAQKLNL PEGVGFKVGK NSPIKYLVLQ VHYAHIDKFK 180
  181 DGSTDDSGVF LDYTEEPRKK LAGTLLLGTD GQIPAMKTEH LETACEVNEQ KVLHPFAYRV 240
  241 HTHGLGKVVS GYRVRTNSDG EQEWLQLGKR DPLTPQMFYN TSNTDPIIEG DKIAVRCTMQ 300
  301 STRHRTTKIG PTNEDEMCNF YLMYYVDHGE TLNMKFCFSQ GAPYYFWSNP DSGLHNIPHI 360
  361 EASTL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..365]	PSI-BLAST	110.0	Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase with bound peptide and dioxygen

Protein Overview: Phm-PB, Phm-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: