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Protein Overview: FBpp0309964, CG5...

General Information:
Name(s) found: FBpp0309964 [FlyBase]
CG5594-PD / FBpp0072046 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=2R:join(19797221..19797356,19799200..19799391,19799711..19799844,19799907..19799989,19800055..19800157,19800252..19800357,19800420..19800549,19800609..19800727,19800791..19801009,19801065..19801221,19801281..19801540,19801602..19801854,19809488..19809850,19809915..19810101,19810164..19810379,19810445..19810552,19811525..19811617,19811939..19812072,19812139..19812278,19812341..19812432); ID=FBpp0309964; name=kcc-PE; parent=FBgn0261794,FBtr0343299; dbxref=FlyBase:FBpp0309964,FlyBase_Annotation_IDs:CG5594-PE; MD5=b728d6fabb5a1e9f3eea7cc56f75b5ca; length=1074; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG5594 (CG5594, FBgn0025698). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19795651..19812619. It has the cytological map location 60A9-60A11. Based on sequence similarity, it is predicted to have molecular function</span>: amino acid transmembrane transporter activity; potassium:chloride symporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: amino acid transport; transport. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1074 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: mechanosensory behavior [IMP]
    sodium ion transport [IEA]
    transmembrane transport [IEA]
    transport [ISS]
    chloride transport [IEA]
    amino acid transport [ISS]
    response to mechanical stimulus [IMP]
    Molecular Function: potassium:chloride symporter activity [ISS]
    amino acid transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDRFQVTKA DEDTALDYNQ DESASGKLLG DIHDETLGEN YGSYDDSGDI HRAEENQKSS  60
   61 IDPNLYLYDD DLETRPHIST FISSIANYEN TIPAATDPDA KPAAPSARMG TLIGVFLPCI 120
  121 QNIFGVILFI RLTWVVGTAG AVCGFLIVLT CCCVTMLTAI SMSAIATNGV VPAGGSYFMI 180
  181 SRSLGPEFGG AVGMLFYTGT TLAAAMYIVG AVEIVLTYMA PWASIFGDFT KDADAMYNNF 240
  241 RVYGTLLLIF MGLIVFLGVK FVNKFATVAL ACVILSIIAV YVGIFDNIHG NEKLYMCVLG 300
  301 KRLLKDIPLE NCTKEDSFLR DIYCPDGKCE EYYLANNVTK VKGIKGLASG VFYDNIFPSF 360
  361 LEKGQFISYG KSAIDIENTS GESYNQIMAD ITTSFTLLIG IFFPSVTGIM AGSNRSGDLA 420
  421 DAQKSIPIGT ICAILTTSTV YLSSVMFFAG TVDNLLLRDK FGQSIGGKLV VANIAWPNQW 480
  481 VILIGSFLST LGAGLQSLTG APRLLQAIAR DEIIPFLAPF AKSSKRGEPT RALLLTIVIC 540
  541 QCGILLGNVD LLAPLLSMFF LMCYGFVNLA CAVQTLLRTP NWRPRFKFYH WSLSLIGLTL 600
  601 CISVMIMTSW YFALIAMGMA IIIYKYIEYR GAEKEWGDGI RGMALTAARY SLLRLEEGPP 660
  661 HTKNWRPQIL VLSKLNDNLL PKYRKIFSFA TQLKAGKGLT ICVSVIKGDH TKITNKAVDA 720
  721 KATLRKYMTD EKVKGFCDVL VAQQIGEGLS SVIQTIGLGG MKPNTVIIGW PYSWRQEGRN 780
  781 SWKTFIQTVR TVAACHMALM VPKGINFYPE SNHKIGGNID IWWIVHDGGL LMLLPFLLKQ 840
  841 HRTWRNCKLR IFTVAQIEDN SIQMKKDLKT FLYHLRIEAD VEVVEMNNSD ISAYTYERTL 900
  901 MMEQRNQMLR ALGLNKKENS KVVQTIVDHH YDATKTASKV RFADPTIEET QHHDSQNDEK 960
  961 RNSIDLDGPE NADTPETTSN KDESTEKADG DFKSSVKPDE FNVRRMHTAI KLNEVIVEKS1020
 1021 QDAQLVIMNL PGPPREVRAE RERNYMEFLE VLTEGLEKVL MVRGGGREVI TIYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..110] deduced N/A No confident structure predictions are available.
    2 View Details [111..579] PSI-BLAST 10.39794 Cytochrome O ubiquinol oxidase, subunit I
    3 View Details [580..655] deduced N/A No confident structure predictions are available.
    4 View Details [656..887] MSA 1.22996 View MSA. No confident structure predictions are available.
    5 View Details [888..989] deduced N/A No confident structure predictions are available.
    6 View Details [990..1074] MSA 1.067993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.93719418697328 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  6.67949994760371 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  6.50939400533716 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  6.40081133240949 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  6.02701109829891 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.9695962563814 bayes_pls_golite062009
  • transporter activity
    		•  4.2806100513341 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.19885907933483 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  4.09889747645813 bayes_pls_golite062009
  • binding
    		•  1.32681091506724 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  1.27735515053931 bayes_pls_golite062009
  • copper ion binding
    		•  1.08782819178001 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  0.803860393147327 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  0.803860393147327 bayes_pls_golite062009
  • cytochrome-c oxidase activity
    		•  0.803860393147327 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.349031670056176 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.336122020727214 bayes_pls_golite062009
  • protein binding
    		•  0.335149649581279 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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