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Protein Overview: CG4091-PA, CG4091-PB

General Information:
Name(s) found: CG4091-PB / FBpp0072007 [FlyBase]
CG4091-PA / FBpp0072005 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4091 (CG4091, FBgn0034894). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19586469..19589924. It has the cytological map location 59F6. Based on sequence similarity, it is predicted to have molecular function</span>: caspase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG4091 (CG4091, FBgn0034894). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19586469..19589924. It has the cytological map location 59F6. Based on sequence similarity, it is predicted to have molecular function</span>: caspase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 188 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS]
    Biological Process: autophagic cell death [IEP]
    salivary gland cell autophagic cell death [IEP]
    negative regulation of anti-apoptosis [ISS]
    Molecular Function: caspase inhibitor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADNVFKSHD IGLRAQKKIL SRMATKNIAK TFIDGTTASL LDNLYRLCKM HTGNKAKAEK  60
   61 LIKNIIKIVI KIGVLHRNNQ FSDEELQKAE LFKRKFQNTQ LSIISFYEVD FTFDLPYLQK 120
  121 SIAESQVALK SIVQPHLTEK SLGRIDEVFD FFGEEALLET AFRPDSPYRE VMGKIVADIN 180
  181 AAMETGDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..188] Pfam 145.075721 No description for PF05527.2 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle