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Protein Overview: alphaPS5-PA

General Information:
Name(s) found: alphaPS5-PA / FBpp0071972 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Ã?&#142;Ã?±PS5 is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?±PS5 (CG5372, FBgn0034880). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19444333..19447720. It has the cytological map location 59E4. Based on sequence similarity, it is predicted to have molecular function</span>: receptor activity; cell adhesion molecule binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cell adhesion. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1000 amino acids

    Gene Ontology:
    Cellular Component: integrin complex [ISS][NAS]
    Biological Process: cell-matrix adhesion [TAS]
    heterophilic cell-cell adhesion [TAS]
    cell adhesion [ISS]
    Molecular Function: cell adhesion molecule binding [ISS]
    receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFSPLPNRV IDAPKHLKTR MIQVRSSYFG YSLVIRPTSI FVGAPRAQST LESQGSINET  60
   61 GAVYRCPLAS GSCSHYVLND KLNKQFQWLG GSMDGGTKDT DKLLVCAPRF FVPKNKNYGQ 120
  121 MRGICYWVRD TVADTPPLSD VRTISLIPSQ AEEHFMLELG LSAHVTDDNS GFLIGAPGVR 180
  181 SWKGSVLVHR GEDLAAQGSY AVKMLDSWDW VKNHFTYVGY ALSSGYFSSN NRTSLLYVTT 240
  241 APSSVLNTGK AYIFDVVGEI VRKLHVFHGE QLGEYFGYSV VAEDLNGDGL TDVVVSAPLN 300
  301 ALGDSYDVGA IYVFINKGLF KFEKKIIRLP LSSGARFGSS LSKVGDINHD GYNDLAVGAP 360
  361 FAGNGAVFIF LGSEHGLRDE PSQRLDAPSR EPGPYGAHMF GQGLSRGSDI DGNGFNDLAI 420
  421 GAPGAEAVYL YRAYPVVKIH ATVRSESRAI RPEQETITVT ACYRLETTSK ARQMQQQELT 480
  481 FRMTIDELLQ RVSFAPMRTN EVSFQAQAGL SGSCRNFSVG VHYTGGIFTP IDLELHYELA 540
  541 KKIPHSHEAF CESCAVVDPL EPKYATGTLS FMTGCAAHVC VSDLQLSSKD VNSSFIFGSL 600
  601 EVLSFSYEIT NSGEPAYVAQ FNVTSSARLP FAKVPGNCRV RHEVMLCDLN GGRALARGDS 660
  661 ESLTIIFDVT QLSGQSLTIE AAVSSAGMDQ NPKDNTMSTT ISLREYAEID ASGGPIDGHI 720
  721 ALKEYPYSAE VNNSYEFKSH GPSIIDELTV YVDVPIAYTV TGSAGIKSIF NISSLQMQAT 780
  781 HGSELVPIKL YDQTNTLAKE YPLEDSSRRA NRKRRELQQD QYAIMPDVNI SDILTKENLP 840
  841 ANRTLVLDCL RGNWTICVRS QMRVQLKPEQ PIDLRISFKV DLNDFVNTFD YLVIFTNVEM 900
  901 FKEGDSTSIA LKRNLKPNVI FNYSETPLPI WYIILSLIAG HLLLGAMTYI LYKLRFFKRG 960
  961 KKEELKRLLE EHRSETKEPA TDCEGNQEEI NVEMHSDLEN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1000] PSI-BLAST 171.0 Thigh, calf-1 and calf-2 domains of integrin alpha; Integrin alpha N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cell adhesion molecule binding
    		•  4.38909417354069 bayes_pls_golite062009
  • binding
    		•  2.38505574840555 bayes_pls_golite062009
  • protein binding
    		•  1.88268703782377 bayes_pls_golite062009
  • receptor activity
    		•  1.69914965252002 bayes_pls_golite062009
  • integrin binding
    		•  1.46467851042106 bayes_pls_golite062009
  • signal transducer activity
    		•  1.45732457862434 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.45732457862434 bayes_pls_golite062009
  • laminin receptor activity
    		•  0.57752974249266 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.339667043877566 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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