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Protein Overview: vir-PA

General Information:
Name(s) found: vir-PA / FBpp0071946 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene virilizer is referred to in FlyBase by the symbol Dmel\vir (CG3496, FBgn0003977). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19247786..19253777. It has the cytological map location 59D8-59D9. Based on sequence similarity, it is predicted to have molecular function</span>: nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: RNA splicing, via transesterification reactions; border follicle cell migration. 16 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1854 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    integral to membrane [ISS]
    Biological Process: RNA splicing, via transesterification reactions [IMP]
    primary sex determination, soma [NAS]
    dosage compensation [TAS]
    regulation of nuclear mRNA splicing, via spliceosome [TAS]
    border follicle cell migration [IMP]
    sex determination [TAS]
    Molecular Function: nucleic acid binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADVDDGSEL LFFDTFSHEE VTDINLDLVQ FPKPVFITQV RIIPLGARVQ ADFPGGVRLG  60
   61 ATNPSKFDLE FFVNDLGMPA ASAFENLGLL RYNQNDCIHL DCSQEKIVTD GLVLRGWYST 120
  121 ITLAIYGIFT NSVTEPIASP TLPCEPVGPE IANLSGEVLL QEDVLKDEWQ EPMQAELLTA 180
  181 HKGNVSDYDP EDMEYGMSRD HYHQHAEEQE QREMRRLRRS THSTDHSPPP PRRSHTHSES 240
  241 NDREYIRCSR DKGSRDWSRS PEYSSHRSRR KRSERSRSVV DEHKWPRTPP ASIDSPTRPR 300
  301 SPDTMDYEDE DSRSHYKMQS SHYRHSSESL HRGERDRDDE DRSCTPQEQF EPILSDDEII 360
  361 GDDEEDDAVD AAAIAEYERE LEAAAAAAPP AIDAFEPWQK PLLVFEGDMA AHFCKELETL 420
  421 KLLFKKLVLQ TRCENVNAFS EEHGASVDER EQFVYLGEQL NNQLGYLAQH YKRRNFVLQQ 480
  481 FFGNDELHLR QAANVLQIAL SFQAACMQPQ PAFKIRHIKL GARMAELLGS SEELFQHLLK 540
  541 EHKFDIFEAV FRLYHEPYMA LSIKLQLLKA VYALLDTRMG IEHFMGAKNN GYQMIVEAIK 600
  601 TAKLTRTKYA LQAIIKKLHL WEGLESVQIW CRRLFVDRII IPGNRDQMED TVITCQQIEF 660
  661 AFEMLMDALF SSQLSYLQPR RFLPVSKKFE VVTDPTAQRS FGNALQSYLG QNSLAESLLV 720
  721 MLANCKELPA TTYLSMLDLM HTLLRSHVGI DYFVDDAFPV TQTIVAILLG LDEVPRNPEE 780
  781 KEEKAEKSDA EDKAMEVENE AVEAGGEKPT PPTADEEGKP VAAPISVPAP AAAPQVRPRP 840
  841 ILRPVLPRLA RLGIEMSYKV QTRYHLDAIA YAAAAPEYDA VKLATHMHAI YSQTCDPAGR 900
  901 QHTVEVLGLN NNLKIFMDLI KKEQRLQTQR QLSSPGTKYK SPVLSYAVDM VDACVRYCEQ 960
  961 LDYLIEHGGV ILELAKNHET FEPSVSAVLQ EMYVYMKPLE AINVFVYDDI MPLVEVIGRS1020
 1021 LDYLTTFPGD LIMAMRILRY LSISKPLAGQ KAPPVTEELK HRFVALQLYA ADGVQLCIQI1080
 1081 MERLCAYFEQ PGAHAPALMT IQGVHCCQIM LPTLQILREL LSYAILCRDG TYKDLTAIDH1140
 1141 LVKVYYLLYY FPTRCQAGPE VEQCKMEVVQ TLLAYTQPNE QDEESLHKSL WTLMIREVLK1200
 1201 NVDGPAHFIP GLKLLAELLP LPLPMPQPLC DQLQQQHKQR LITERKLWSA HLHPQSGQIA1260
 1261 KLVEALAPSS FPQLSELLQR VCMQLSDLAP NMTLLIAKTI TELLCNEYQT SNCIPTTNLE1320
 1321 RLLRFSTRLC AFAPLKSSML SILSGKFWEL FQSLLALNEF NDVVSNCQEA VHRILDSFLD1380
 1381 SGISLISHKS TASPALNLAA ALPPKELIPR IIDAVFSNLT SVEVTHGISI LAVRNLVILT1440
 1441 EHDFTFYHLA QLLKQKITEF QAWMERVILH NETVEYNANI ESLILLLRSL TQIEPPPAMS1500
 1501 AMPHRTLKLG ATELAQLVEF QDIELAKPPV LSRILTVMEK HKAVANEAAL SDLKQLILLQ1560
 1561 ASKQEILAGT STETPPEAEG EANPSASSCS ASLTVEPYLP QAEGIVTQYE ARPIFTRFCA1620
 1621 TAENAQLTAR YWLDPLPIEL IEDMNEPIYE RIACDLTDLA NVCLNPDLNV AGDSKRVMNL1680
 1681 SGSPQSNREM TPTAPCFRTR RVEVEPATGR PEKKMFVSSV RGRGFARPPP SRGDLFRSRP1740
 1741 PNTSRPPSLH VDDFLALETC GAQPTGPTGY NKIPSMLRGS RVGRNRGSRI SAAAAFRQKK1800
 1801 MMRIGSPSSW AESPGSYRSA SDSHFSSSDS HYSSPHYSGR PRGRGLRSRP SYLR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] MSA 1.339969 View MSA. No confident structure predictions are available.
    2 View Details [141..336] MSA 7.415996 View MSA. No confident structure predictions are available.
    3 View Details [337..405] deduced N/A No confident structure predictions are available.
    4 View Details [406..570] MSA 8.363994 View MSA. No confident structure predictions are available.
    5 View Details [571..811] deduced N/A No confident structure predictions are available.
    6 View Details [812..1048] deduced N/A No confident structure predictions are available.
    7 View Details [1049..1228] deduced N/A No confident structure predictions are available.
    8 View Details [1229..1307] deduced N/A No confident structure predictions are available.
    9 View Details [1308..1500] deduced N/A No confident structure predictions are available.
    10 View Details [1501..1629] deduced N/A No confident structure predictions are available.
    11 View Details [1630..1854] MSA 1.020972 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

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