Protein Overview: nahoda-PA, nahoda-PB

General Information:
Name(s) found:	nahoda-PB / FBpp0071854 [FlyBase] nahoda-PA / FBpp0071853 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24658811\|ref\|NP_726264.1\| nahoda, isoform B [Drosophila melanogaster] [NCBI NR] gi\|24658804\|ref\|NP_523815.2\| nahoda, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23240118\|gb\|AAN16114.1\| nahoda, isoform B [Drosophila melanogaster] [NCBI NR] gi\|21626572\|gb\|AAF46927.2\| nahoda, isoform A [Drosophila melanogaster] [NCBI NR] gi\|16767924\|gb\|AAL28180.1\| GH04942p [Drosophila melanogaster] [NCBI NR] The gene nahoda is referred to in FlyBase by the symbol Dmel\nahoda (CG12781, FBgn0034797). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18783696..18804247. It has the cytological map location 59B4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: dopamine beta-monooxygenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: histidine catabolic process. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG12781-PB translation from_gene[CG12781 nahoda FBgn0034797] seq_release:3 mol_weight=149942 cds_boundaries:(2R:17,947,846..17,959,654[+]) aa_length:1335 transcript_info:[CG12781-RB seq_release:3] gene_info:[gene symbol:nahoda FBgn0034797 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta] >CG12781-PA translation from_gene[CG12781 nahoda FBgn0034797] seq_release:3 mol_weight=149942 cds_boundaries:(2R:17,947,846..17,959,654[+]) aa_length:1335 transcript_info:[CG12781-RA seq_release:3] gene_info:[gene symbol:nahoda FBgn0034797 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta] (Q9W1X5) CG12781 protein (GH04942p) [DrosMelano7227.FASTAC.txt] CG12781-PB, isoform B [Drosophila melanogaster]gi\|21626572\|gb\|AAF46927.2\| CG12781-PA, isoform A [Drosophila melanogaster]gi\|16767924\|gb\|AAL28180.1\| GH04942p [Drosophila melanogaster]gi\|24658811\|ref\|NP_726264.1\| CG12781-PB [Drosophila melanogaster]gi\|2 [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071853; name=nahoda-PA; paren [fly-100309-contam.fasta] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071854; name=nahoda-PB; paren [fly-100309-contam.fasta] nahoda CG12781-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG12781-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] nahoda CG12781-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG12781-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] GH04942p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071853; name=nahoda-PA; parent=FBgn0034797,FBtr0071942; dbxref=FlyBase:FBpp0071853,FlyBase_Annotation_IDs:CG12781-PA,GB_protein:AAF46927.2,REFSEQ:NP_523815,GB_protein:AAF46927; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071854; name=nahoda-PB; parent=FBgn0034797,FBtr0071943; dbxref=FlyBase:FBpp0071854,FlyBase_Annotation_IDs:CG12781-PB,GB_protein:AAN16114.1,REFSEQ:NP_726264,GB_protein:AAN16114; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071853; name=nahoda-PA; parent=FBgn0034797,FBtr0071942; dbxref=FlyBase:FBpp0071853,FlyBase_Annotation_IDs:CG12781-PA,GB_protein:AAF46927.2,REFSEQ:NP_523815,GB_protein:AAF46927; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071854; name=nahoda-PB; parent=FBgn0034797,FBtr0071943; dbxref=FlyBase:FBpp0071854,FlyBase_Annotation_IDs:CG12781-PB,GB_protein:AAN16114.1,REFSEQ:NP_726264,GB_protein:AAN16114; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] GH04942p OS=Drosophila melanogaster GN=nahoda PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071853; name=nahoda-PA; parent=FBgn0034797,FBtr0071942; dbxref=FlyBase:FBpp0071853,FlyBase_Annotation_IDs:CG12781-PA,GB_protein:AAF46927.2,REFSEQ:NP_523815,GB_protein:AAF46927,FlyMine:FBpp0071853,modMine:FBpp0071853; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:join(18791801..18791996,18798036..18798106,18798345..18798442,18798499..18799871,18799940..18800383,18800513..18801085,18801140..18801356,18801419..18801639,18801702..18801871,18802968..18803612); ID=FBpp0071854; name=nahoda-PB; parent=FBgn0034797,FBtr0071943; dbxref=FlyBase:FBpp0071854,FlyBase_Annotation_IDs:CG12781-PB,GB_protein:AAN16114.1,REFSEQ:NP_726264,GB_protein:AAN16114; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071853; name=nahoda-PA; parent=FBgn0034797,FBtr0071942; dbxref=FlyBase:FBpp0071853,FlyBase_Annotation_IDs:CG12781-PA,GB_protein:AAF46927.2,REFSEQ:NP_523815,GB_protein:AAF46927,FlyMine:FBpp0071853,modMine:FBpp0071853; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071854; name=nahoda-PB; parent=FBgn0034797,FBtr0071943; dbxref=FlyBase:FBpp0071854,FlyBase_Annotation_IDs:CG12781-PB,GB_protein:AAN16114.1,REFSEQ:NP_726264,GB_protein:AAN16114; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071853; name=nahoda-PA; parent=FBgn0034797,FBtr0071942; dbxref=FlyBase:FBpp0071853,FlyBase_Annotation_IDs:CG12781-PA,GB_protein:AAF46927.2,REFSEQ:NP_523815,GB_protein:AAF46927,FlyMine:FBpp0071853,modMine:FBpp0071853; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071854; name=nahoda-PB; parent=FBgn0034797,FBtr0071943; dbxref=FlyBase:FBpp0071854,FlyBase_Annotation_IDs:CG12781-PB,GB_protein:AAN16114.1,REFSEQ:NP_726264,GB_protein:AAN16114; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] GH04942p OS=Drosophila melanogaster GN=nahoda PE=1 SV=2 [DROME.fasta.20160308] FBpp0071853 type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071853; name=nahoda-PA; parent=FBgn0034797,FBtr0071942; dbxref=FlyBase:FBpp0071853,FlyBase_Annotation_IDs:CG12781-PA,GB_protein:AAF46927.2,REFSEQ:NP_523815,GB_protein:AAF46927,FlyMine:FBpp0071853,modMine:FBpp0071853; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0071854 type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071854; name=nahoda-PB; parent=FBgn0034797,FBtr0071943; dbxref=FlyBase:FBpp0071854,FlyBase_Annotation_IDs:CG12781-PB,GB_protein:AAN16114.1,REFSEQ:NP_726264,GB_protein:AAN16114; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071853; name=nahoda-PA; parent=FBgn0034797,FBtr0071942; dbxref=FlyBase:FBpp0071853,FlyBase_Annotation_IDs:CG12781-PA,GB_protein:AAF46927.2,REFSEQ:NP_523815,GB_protein:AAF46927,UniProt/TrEMBL:Q9W1X5,FlyMine:FBpp0071853,modMine:FBpp0071853; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2R:join(22904278..22904473,22910513..22910583,22910822..22910919,22910976..22912348,22912417..22912860,22912990..22913562,22913617..22913833,22913896..22914116,22914179..22914348,22915445..22916089); ID=FBpp0071854; name=nahoda-PB; parent=FBgn0034797,FBtr0071943; dbxref=FlyBase:FBpp0071854,FlyBase_Annotation_IDs:CG12781-PB,GB_protein:AAN16114.1,REFSEQ:NP_726264,GB_protein:AAN16114,UniProt/TrEMBL:Q9W1X5; MD5=2ef539a35329f118c83860fe6eb461e1; length=1335; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1335 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	histidine catabolic process [IEA]
Molecular Function:	dopamine beta-monooxygenase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIQSTRHSP FAWTARALLL LATWCCYLGY LGSEAHVALT YPPARKFDLD FLDNARTKAP  60
   61 CGMPKGSIRT SLLSGTQFNV TWHLAYAHKG GFRLQLLDAL DRPVLDLTPH VNNSEFVSTD 120
  121 VTAQSYQVKI PNDFECYNCT LRLLRQADEW TTSYRFWSCA DVDIKLRKDF KETCSGNGKY 180
  181 FPSRCKCDKN FYGPQCQYKD ECSADSDCGV QGKCVELGGT SLPKKQCYCN FGWFGIGCNK 240
  241 RSPYKSTSLD LSSYSKKELS PDYHVYWRLL EEQKEIEMVL KVNGTSWVGL GWRPRGMTPE 300
  301 CKNFPLIRDI GDLTTTLEAS VPEPKSEPEP KSEPEPKSEP EPKSEPEPKS EPEPKSEPEP 360
  361 KSEPEPKSEP EPKSEPEPKS EPEPKSEPEP KSEPEPKSEP EPKSEPEPKS EPEPKSEPEP 420
  421 KSEPQPKQLA ELRAAPEPQS EPEPKSEPEP KSEPEPKSEP EPKSEPEPKS EPEPKSEPEP 480
  481 KSEPEPKSEP EPTSEPEPKS APEPKSEPEP TSEPEPTSKP EPTSEPEPKS EPEPKSEPEA 540
  541 QSSKSKRVAG DFAKKGVSSV STSVSYRVST KSDRQRREAD SPKYRLNPYT PRHDFNGMDC 600
  601 TDIVIGAARG MASRVGDYYS RDRSTPHTDE FFGGKSNLAL GTGFEENGVT TIIFRKKLVA 660
  661 NEPTDHTLDD ALTHVIWAKG QEPEAYVHVP ASGLETQIAT VKNFYQQDEL KYHGHQMQRG 720
  721 VTQINFFEKE KSATSTDRND LGTNVLDNDC YGHWKYPSNC SPQEHTCEYY ASWETVGKGD 780
  781 EMRWHIETSN TQTWTGIGFS DDQRMSQTDA IIGWVDGRSG RPFLMDTWVL GYAPPKLDDR 840
  841 QDIYNASGRI EKGVTILEFN RKRVSNDEQD LSFTDDHCLY LFFPVLGGAF NVVNKKIRKH 900
  901 EQVPPISSQR VCIKSCGKEL ESVFVGTSTP APSRLVYAVA VKLMNLGESY EAPKPGTVEF 960
  961 NNLAATISDS FNGILSPLTG YYKTEILGFE KEGSTMVAKV QAMFDKADVE KKHALETNEV1020
 1021 DKTSEAAAQK NADVIRSALK DQVATGRVGS LTVDPQFLDF EALEYKSSSE PNAKETLLSF1080
 1081 FDLSETRLYI VLGLIAALVL IALIQAFCTI WKTSRKSKNT KEKLIQNSPW KEFASNTNYA1140
 1141 FDPYGETEEK NITNSSSGKE KARNRHQSTT SSQQTTLPMS HSPTSKSQMY YESPNGQGKS1200
 1201 SNGNGSRGNG RATQESSVGG APYSRSSYAE RAYSLPRQAH QYQQSPASMQ PSGYYTHDRR1260
 1261 AARQGSRDRE REREREEERR QRQDRDRDSG YDRSRDDPRQ NGGSDTPDFY FMPSQRKYSG1320
 1321 EVVRVYVDYN KDPKH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..133]	deduced	N/A	No confident structure predictions are available.
2	View Details	[134..255]	PSI-BLAST	6.39794	Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
3	View Details	[256..527]	MSA	3.285996	View MSA. No confident structure predictions are available.
4	View Details	[528..610]	deduced	N/A	No confident structure predictions are available.
5	View Details	[611..748]	MSA	2.235995	View MSA. No confident structure predictions are available.
6	View Details	[749..926]	MSA	5.048976	View MSA. No confident structure predictions are available.
7	View Details	[927..1144]	deduced	N/A	No confident structure predictions are available.
8	View Details	[1145..1335]	deduced	N/A	No confident structure predictions are available.

Protein Overview: nahoda-PA, nahoda-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: