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Protein Overview: comr-PA

General Information:
Name(s) found: comr-PA / FBpp0071651 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene cookie monster is referred to in FlyBase by the symbol Dmel\comr (CG13493, FBgn0034667). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17752372..17754364. It has the cytological map location 58A3. There is experimental evidence that it has the molecular function</span>: transcription activator activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of transcription from RNA polymerase II promoter; spermatogenesis. 3 alleles are reported. The phenotypes of these alleles are annotated with: spermatid; testis; meiotic cell cycle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 600 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    chromatin [NAS]
    Biological Process: spermatogenesis [IMP]
    positive regulation of transcription from RNA polymerase II promoter [IMP]
    Molecular Function: transcription activator activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGNQDTLGQ SQQVNESGDE YEEDAATSWT NELEQQESRT PADSPEFLDF VDSEDPLEDF  60
   61 ERNPLQKEPL DLAVKPVSDI NKKAAENHRR IYRQLGIHIP ETPKSHPLLH YAFVVKLFLA 120
  121 TDNSSIHYLK WSANGRELEV DYQGMQEHLS SGCSMFHCRN TLQFTGTLLA HGFERVSLKD 180
  181 VRKSSATNIT LIYRNPNFVK GQLLKLHKLA QECEKIPEIS SPGTAEPRRP PLHLPNYAHI 240
  241 SRMVRRGDLC STPYTSRSAL QVARCHFQTL LGYQADLGVL KDRNNHDMFN KNIMTQLNVK 300
  301 RGRSSINNAP VDLAPSKVSF EKFVKPHESV INIGIGQAPD YAGYYGQVEL FKVNEFFSEY 360
  361 LPRYGSKITG YKEIVMDATN KSIGFQQNLP IGMNYSDDED DALPPISSDL DLDFMPSTSA 420
  421 AAKMKSTGRK VVEDSDLEQA MQELCGGSNL NEEEELPQTS TRFKAKPKPR AKTKAKPTKR 480
  481 QAKPVHSSSS ECEDFKPDEV YEGFKSRNPK NVKLKPSDEN ISYTLEEGTD FEEQVIEETT 540
  541 ETKVQDSQYD DLDDDDDDEE EDYFDEDDED YVYKNLQYRN PPEPPKSRRY DLRNSKRNPR 600
  601

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] deduced N/A No confident structure predictions are available.
    2 View Details [103..232] FFAS03 5.43 SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
    3 View Details [233..404] deduced N/A No confident structure predictions are available.
    4 View Details [405..600] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.23858959608048 bayes_pls_golite062009
  • DNA binding
    		•  4.78517210147551 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.72059012764202 bayes_pls_golite062009
  • transcription factor activity
    		•  4.02736190679869 bayes_pls_golite062009
  • transcription activator activity
    		•  3.46623224639317 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.31558616762587 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.41045867230388 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.9708626903609 bayes_pls_golite062009
  • protein binding
    		•  1.77689943618029 bayes_pls_golite062009
  • transcription factor binding
    		•  0.752335897765285 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.490809930581315 bayes_pls_golite062009
  • structural molecule activity
    		•  0.128347187436068 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.0406721670764369 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle