Protein Overview: CG10306-PA

General Information:
Name(s) found:	CG10306-PA / FBpp0071587 [FlyBase]
Description(s) found: Found 24 descriptions. SHOW ALL	This gene is referred to in FlyBase by the symbol Dmel\CG10306 (CG10306, FBgn0034654). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17572775..17573709. It has the cytological map location 57F8. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	222 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] eukaryotic translation initiation factor 3 complex [IEA][ISS]
Biological Process:	translational initiation [ISS] regulation of translational initiation [IEA]
Molecular Function:	translation initiation factor activity [IEA][ISS] ribosome binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHLVKMENG QSQTIQEMLG CIERYNPDHL KTLESYVQDQ AKNNTYDLEA NLAVLKLYQF  60
   61 NPHMLNFDIT YTILLKSLTS LPHTDFVMAK CLLLPQQMKD ENVQTIIDLA DILERADFTL 120
  121 FWQRAEVNRN MFRHITGFHD SIRKFVSHVV GTTFQTIRKD LLKELLGGIE DSTLESWIKR 180
  181 NGWKNQGQGL VIVAMQDDKI KTKNITEKIE FDNVGALMAQ CL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
translation initiation factor activity	4.65136805471804	bayes_pls_golite062009
binding	2.27902748675387	bayes_pls_golite062009
protein binding	1.94427330399472	bayes_pls_golite062009
RNA cap binding	1.73309326409609	bayes_pls_golite062009
sequence-specific DNA binding	0.93130370844712	bayes_pls_golite062009
structural molecule activity	0.908029258648777	bayes_pls_golite062009
nucleic acid binding	0.856241051862415	bayes_pls_golite062009
translation regulator activity	0.82193201542158	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.803700928110921	bayes_pls_golite062009
structural constituent of ribosome	0.742648546865457	bayes_pls_golite062009
transcription repressor activity	0.67795138236883	bayes_pls_golite062009
RNA binding	0.39193569533369	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.10854873707001	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..222]	PSI-BLAST	94.0	Crystal Structure of Human eIF3k

Protein Overview: CG10306-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: