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Protein Overview: CG8654-PA, FBpp0...

General Information:
Name(s) found: FBpp0309574 [FlyBase]
FBpp0296957 [FlyBase]
FBpp0296956 [FlyBase]
CG8654-PA / FBpp0085642 [FlyBase]
Description(s) found:
Found 38 descriptions.
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  • type=protein; loc=2R:join(15869814..15870208,15870411..15870554,15870617..15871586); ID=FBpp0309574; name=CG8654-PD; parent=FBgn0034479,FBtr0342667; dbxref=FlyBase:FBpp0309574,FlyBase_Annotation_IDs:CG8654-PD; MD5=127acdec7f7c603d0318a1e0394a9a4d; length=502; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:join(15869814..15870208,15870411..15870554,15870617..15871586); ID=FBpp0296957; name=CG8654-PC; parent=FBgn0034479,FBtr0305677; dbxref=REFSEQ:NP_001246442,GB_protein:AFH08195,FlyBase:FBpp0296957,FlyBase_Annotation_IDs:CG8654-PC; MD5=127acdec7f7c603d0318a1e0394a9a4d; length=502; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:join(15869814..15870208,15870411..15870554,15870617..15871586); ID=FBpp0296956; name=CG8654-PB; parent=FBgn0034479,FBtr0305676; dbxref=REFSEQ:NP_001246441,GB_protein:AFH08194,FlyBase:FBpp0296956,FlyBase_Annotation_IDs:CG8654-PB; MD5=127acdec7f7c603d0318a1e0394a9a4d; length=502; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8654 (CG8654, FBgn0034479). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15868574..15872262. It has the cytological map location 56F4. Based on sequence similarity, it is predicted to have molecular function</span>: secondary active organic cation transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 502 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    Molecular Function: secondary active organic cation transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADRPQDPKA PKPLKPVTKT GDPIISQIGD FRRYQLFFFF IVLLCKFGTG WHTLGHIFLA  60
   61 APTPLSCKTE NVTDPCSDEC SETEFDTSVF QSTIITEWNL TCESKQLASL SQSIVMLGIL 120
  121 FGSILFGMFA DRYGRRPAFL TCCFMQLITG LIVCVSPYYW FYCLFRFLVA VATAGTMTTS 180
  181 FVLLMEIVGP KKREMVAILY QIPFNIGHAS LALFAYFIRE WRWFQFSITI FSIVFVIYIW 240
  241 LVPESPRWLF TTGKLDKSIK ILEKIAKCNK APTETIRPEI EAAYGALAAR QPVKKGTVVD 300
  301 LFRTPYMRIK TIFMANNWLV VCMVYYGTAQ YVSALGGNIF ISNAIAAGVG IPGTCLCALM 360
  361 TKYLGRKKTL LLSNGCSALG LILLACLSTQ AEAVRVTCAT IGLFGASITF PNVYLYGGEL 420
  421 FPTVVRSSGV GLCSMVGRIG SIVAPLIVDL AAYGLWVAPL IFGIFSILAM LGTIFLPETR 480
  481 GTPLPETLED GETFGRKKKD QA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..502] PSI-BLAST 29.30103 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  3.3413526350788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.21476253433572 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.29370920212213 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.29370920212213 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.47932844880848 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.01649151876552 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle