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Protein Overview: CG15117-PA

General Information:
Name(s) found: CG15117-PA / FBpp0085777 [FlyBase]
Description(s) found:
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  • gi|21626964|gb|AAF57602.2| CG15117, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|19922582|ref|NP_611395.1| CG15117, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|17861994|gb|AAL39474.1| LD04718p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG15117 (CG15117, FBgn0034417). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15009735..15016746. It has the cytological map location 56B5. Based on sequence similarity, it is predicted to have molecular function</span>: beta-glucuronidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • >CG15117-PA translation from_gene[CG15117 CG15117 FBgn0034417] seq_release:3 mol_weight=75168 cds_boundaries:(2R:14,186,170..14,192,720[-]) aa_length:656 transcript_info:[CG15117-RA seq_release:3] gene_info:[gene symbol:CG15117 FBgn0034417 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V8R0) CG15117 protein (LD04718p) [DrosMelano7227.FASTAC.txt]
  • CG15117-PA, isoform A [Drosophila melanogaster]gi|17861994|gb|AAL39474.1| LD04718p [Drosophila melanogaster]gi|19922582|ref|NP_611395.1| CG15117-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(15009952..15010118,15010177..15010315,15010415..15010591,15010653..15010737,15010800..15010943,15011004..15011541,15011610..15011922,15012042..15012445,15016502..15016505); ID=FBpp0085777; name=CG15117-PA; parent=FBgn003441 [fly-100309-contam.fasta]
  • CG15117-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD04718p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(15009952..15010118,15010177..15010315,15010415..15010591,15010653..15010737,15010800..15010943,15011004..15011541,15011610..15011922,15012042..15012445,15016502..15016505); ID=FBpp0085777; name=CG15117-PA; parent=FBgn0034417,FBtr0086593; dbxref=FlyBase_Annotation_IDs:CG15117-PA,FlyBase:FBpp0085777,GB_protein:AAF57602.2,REFSEQ:NP_611395,GB_protein:AAF57602; MD5=98d6ff9784d51374b61f3966d144a58d; length=656; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(15009952..15010118,15010177..15010315,15010415..15010591,15010653..15010737,15010800..15010943,15011004..15011541,15011610..15011922,15012042..15012445,15016502..15016505); ID=FBpp0085777; name=CG15117-PA; parent=FBgn0034417,FBtr0086593; dbxref=FlyBase_Annotation_IDs:CG15117-PA,FlyBase:FBpp0085777,GB_protein:AAF57602.2,REFSEQ:NP_611395,GB_protein:AAF57602; MD5=98d6ff9784d51374b61f3966d144a58d; length=656; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG15117, isoform A OS=Drosophila melanogaster GN=CG15117 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(15009952..15010118,15010177..15010315,15010415..15010591,15010653..15010737,15010800..15010943,15011004..15011541,15011610..15011922,15012042..15012445,15016502..15016505); ID=FBpp0085777; name=CG15117-PA; parent=FBgn0034417,FBtr0086593; dbxref=FlyBase_Annotation_IDs:CG15117-PA,FlyBase:FBpp0085777,GB_protein:AAF57602.2,REFSEQ:NP_611395,GB_protein:AAF57602,FlyMine:FBpp0085777,modMine:FBpp0085777; MD5=98d6ff9784d51374b61f3966d144a58d; length=656; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(19128997..19129000,19124537..19124940,19124105..19124417,19123499..19124036,19123295..19123438,19123148..19123232,19122910..19123086,19122672..19122810,19122447..19122613)); ID=FBpp0085777; name=CG15117-PA; parent=FBgn0034417,FBtr0086593; dbxref=FlyBase_Annotation_IDs:CG15117-PA,FlyBase:FBpp0085777,GB_protein:AAF57602.2,REFSEQ:NP_611395,GB_protein:AAF57602,FlyMine:FBpp0085777,modMine:FBpp0085777; MD5=98d6ff9784d51374b61f3966d144a58d; length=656; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(19128997..19129000,19124537..19124940,19124105..19124417,19123499..19124036,19123295..19123438,19123148..19123232,19122910..19123086,19122672..19122810,19122447..19122613)); ID=FBpp0085777; name=CG15117-PA; parent=FBgn0034417,FBtr0086593; dbxref=FlyBase_Annotation_IDs:CG15117-PA,FlyBase:FBpp0085777,GB_protein:AAF57602.2,REFSEQ:NP_611395,GB_protein:AAF57602,FlyMine:FBpp0085777,modMine:FBpp0085777; MD5=98d6ff9784d51374b61f3966d144a58d; length=656; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A1ZBG9, Beta-glucuronidase OS=Drosophila melanogaster GN=CG15117 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0085777 type=protein; loc=2R:complement(join(19128997..19129000,19124537..19124940,19124105..19124417,19123499..19124036,19123295..19123438,19123148..19123232,19122910..19123086,19122672..19122810,19122447..19122613)); ID=FBpp0085777; name=CG15117-PA; parent=FBgn0034417,FBtr0086593; dbxref=FlyBase_Annotation_IDs:CG15117-PA,FlyBase:FBpp0085777,GB_protein:AAF57602.2,REFSEQ:NP_611395,GB_protein:AAF57602,FlyMine:FBpp0085777,modMine:FBpp0085777; MD5=98d6ff9784d51374b61f3966d144a58d; length=656; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(19128997..19129000,19124537..19124940,19124105..19124417,19123499..19124036,19123295..19123438,19123148..19123232,19122910..19123086,19122672..19122810,19122447..19122613)); ID=FBpp0085777; name=CG15117-PA; parent=FBgn0034417,FBtr0086593; dbxref=FlyBase_Annotation_IDs:CG15117-PA,FlyBase:FBpp0085777,GB_protein:AAF57602.2,REFSEQ:NP_611395,GB_protein:AAF57602,UniProt/TrEMBL:Q7K173,FlyMine:FBpp0085777,modMine:FBpp0085777; MD5=98d6ff9784d51374b61f3966d144a58d; length=656; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 656 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: carbohydrate metabolic process [IEA]
    Molecular Function: cation binding [IEA]
    beta-glucuronidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALSIFSLVT GLYVLHFSIA LILVNKEVPQ TRGMLYPRES ETREVRSLDG IWNFVRSDQA  60
   61 NPTQGVRDEW YAKELSKSRP TIPMPVPASY NDITTDNLRD HVGTVWYDRK FFVPRSWSKD 120
  121 QRIWLRFGSV HYEAYVWING QKVVKHEMGH LPFEAEVTDL LSYGAENRIT VMCDNALIQT 180
  181 TVPQGRITEV PNDGGMTIVQ SYTFDFFNYA GIHRSVHLYT TPRTFIEEVE VTTNLSKDAT 240
  241 VGEVFYSVSV NGSAANEADN VLQIQANLYD KDGILVANAT SDQKLGGKLQ VNPVKPWWPY 300
  301 LMHSEPGYLY QLEIKLLATN DELLDVYRLK VGIRTLSWNS QQFLINGKPV YFRGFGRHED 360
  361 SDIRGKGLDN ALMVRDFNLL KWIGANAYRT SHYPYSEESM QFADEHGIMI IDECPSVDTE 420
  421 NFSQELLGKH KSSLEQLIHR DRNHPSVVMW SIANEPRTGS VSADSYFELV ANFTRSLDKT 480
  481 RPITAAIAVS NTQDKAGRSL DIISFNRYNA WYSNAGRLDM ITQNVIDEAI AWNKRYNKPI 540
  541 IMSEYGADTL EGLHMQPAYV WSEEFQTEVF SRHFKAFDEL RKKGWFIGEF VWNFADFKTA 600
  601 QSYTRVGGNK KGVFTRARQP KAAAHLLRKR YFALGRDLDQ CSFPEDLFTY IADLIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..656] PSI-BLAST 127.0 beta-Glucuronidase; beta-Glucuronidase, domain 3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  6.26329339735894 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  5.92180849080637 bayes_pls_golite062009
  • hydrolase activity
    		•  3.98075336331567 bayes_pls_golite062009
  • hexosaminidase activity
    		•  3.21852337137039 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  2.69072465526737 bayes_pls_golite062009
  • hyalurononglucosaminidase activity
    		•  2.33846657668199 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • glucosidase activity
    		•  1.85545420386612 bayes_pls_golite062009
  • galactosidase activity
    		•  1.26155841119987 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  1.00973231642658 bayes_pls_golite062009
  • peptidase activity
    		•  0.618122797487524 bayes_pls_golite062009
  • binding
    		•  0.601963252939415 bayes_pls_golite062009
  • beta-glucuronidase activity
    		•  0.55376725638834 bayes_pls_golite062009
  • sugar binding
    		•  0.52048704356718 bayes_pls_golite062009
  • mannosidase activity
    		•  0.48536369022293 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.340224150705178 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.31275257729319 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • fucose binding
    		•  0.0946432585122601 bayes_pls_golite062009
  • beta-galactosidase activity
    		•  0.0137149865738109 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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