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Protein Overview: FBpp0311551, l(2...

General Information:
Name(s) found: FBpp0311551 [FlyBase]
l(2)08717-PA / FBpp0085817 [FlyBase]
l(2)08717-PB / FBpp0085816 [FlyBase]
Description(s) found:
Found 39 descriptions.
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  • type=protein; loc=2R:complement(14684984..14685160,14685221..14686297,14686578..14686768,14689523..14689571); ID=FBpp0311551; name=l(2)08717-PC; parent=FBgn0010651,FBtr0345426; dbxref=FlyBase:FBpp0311551,FlyBase_Annotation_IDs:CG15095-PC; MD5=fa73f8f0e9d1a4201dcbbbd9eceef940; length=497; release=r5.56; species=Dmel; [FlyBase]
  • The gene lethal (2) 08717 is referred to in FlyBase by the symbol Dmel\l(2)08717 (CG15095, FBgn0010651). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14684769..14691232. It has the cytological map location 55F3-55F4. Based on sequence similarity, it is predicted to have molecular function</span>: high affinity inorganic phosphate:sodium symporter activity. There is experimental evidence that it is involved in the biological process</span>: response to hypoxia; wing disc dorsal/ventral pattern formation. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene lethal (2) 08717 is referred to in FlyBase by the symbol Dmel\l(2)08717 (CG15095, FBgn0010651). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14684769..14691232. It has the cytological map location 55F3-55F4. Based on sequence similarity, it is predicted to have molecular function</span>: high affinity inorganic phosphate:sodium symporter activity. There is experimental evidence that it is involved in the biological process</span>: response to hypoxia; wing disc dorsal/ventral pattern formation. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 497 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: transmembrane transport [IEA]
    response to hypoxia [IEP][IMP]
    wing disc dorsal/ventral pattern formation [IGI]
    Molecular Function: high affinity inorganic phosphate:sodium symporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTALTMVKT GGKYANEKFF GVRHVQCILC FFCLAMSYAW RVNLSVALVA MTDNSTSLAQ  60
   61 NNTNTGVAPS EPGFDFFNSE RYYNFTQKEK GNLQASFFFG YIVTQVPGGY IAQRYGAKTM 120
  121 LMYGLGIAAL ITMLSPMSLQ FGWVALAVMR FVMGLAQGAV HPATHALLAK WSPADERGML 180
  181 GTLCYSGAQF GTVVMLATSG FIADSVLGWP SIFYLGGACG FIWMVFWYLF SASTPEEHRL 240
  241 ISPGELKYIT DSRSDGKMQS AEKLAPTPWK AIFSSLPFLS LLVVHCTHIF GYWLLLMQIP 300
  301 TYMKKIYHVD IKKGALLSSL PYMVMLLLSF FFVWLSKVLQ KKEGMSLSFN RKIFNSIGHW 360
  361 IPMLSLIALG YVPADNAPLA VTLLTLTVGI SGATYLGFQV NHIDLSPNYA GTLMGITNCA 420
  421 ANVMSGIAPV IVGQIVVDET SVTEWRLVFL LAAAFYFLGN LLFVIFGRTE VQWWDSPRDN 480
  481 KEDAEQGTPL APNGQVK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..497] PSI-BLAST 45.522879 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.6188895673796 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.6188895673796 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.78662033436109 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.02928844080554 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle