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Protein Overview: FBpp0303030, CG5...

General Information:
Name(s) found: FBpp0303030 [FlyBase]
CG5757-PA / FBpp0085966 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=2R:complement(13981418..13981604,13981670..13982036,13982089..13982170); ID=FBpp0303030; name=CG5757-PB; parent=FBgn0034299,FBtr0329995; dbxref=FlyBase:FBpp0303030,FlyBase_Annotation_IDs:CG5757-PB,REFSEQ:NP_001261065,GB_protein:AGB93597; MD5=a275d8d40417c4516a4675fb086ed293; length=211; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG5757 (CG5757, FBgn0034299). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13981233..13982212. It has the cytological map location 55B4. Based on sequence similarity, it is predicted to have molecular function</span>: thymidylate kinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: dTDP biosynthetic process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 211 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: dTDP biosynthetic process [IEA]
    Molecular Function: thymidylate kinase activity [ISS]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAGKRGALI IFEGCDRSGK TTQSRLLVEL LKSKGIPTLP MNFPERSSSI GQVINSYLTN  60
   61 SKDLPDEVIH LMFSANRWEH INQVKEKLLE GTTLVVDRYS FSGVAYSAAK GLDFDWCYAP 120
  121 ERGLIKPDAV FYLRAPPNDL THRGQYGKER YEKVEFQGRV AEVFNRICSK EGSYFHQFDA 180
  181 RQSVEDLHAQ IASITEELLP KVATRPLDTL S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] PSI-BLAST 38.154902 Thymidylate kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.66392587433723 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.01286198424677 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  2.24094813695083 bayes_pls_golite062009
  • kinase activity
    		•  2.0779386406753 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.06460241490722 bayes_pls_golite062009
  • binding
    		•  2.05253348982328 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.0114051513686 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.96697952975573 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.92626167278464 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.9136419736217 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.6854386921174 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.64467072658718 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.5008821138859 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.49633029954726 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.49611313354225 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • helicase activity
    		•  1.16085745407703 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA binding
    		•  0.967303417236485 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.748437190903548 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.720649395550746 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.58862275163252 bayes_pls_golite062009
  • adenylate kinase activity
    		•  0.447752711852745 bayes_pls_golite062009
  • CTP synthase activity
    		•  0.435702031552231 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  0.3625050107782 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.27925703205288 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.22150712609541 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • DNA polymerase activity
    		•  4.95561462330096E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle