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Protein Overview: mbl-PB

General Information:
Name(s) found: mbl-PB / FBpp0086144 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene muscleblind is referred to in FlyBase by the symbol Dmel\mbl (CG33197, FBgn0053197). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13153058..13263374. It has the cytological map location 54B1-54B5. It is reported to have molecular function</span>: DNA binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: compound eye photoreceptor cell differentiation; muscle organ development; embryonic development. 36 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; peripheral nervous system; nervous system; cytoplasmic part; organ system; contractile fiber part; adult segment; compound cell cluster organ; adult mesothoracic segment; sarcomere. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 297 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    Biological Process: compound eye photoreceptor cell differentiation [IMP][NAS][TAS]
    muscle organ development [IMP]
    embryonic development [IMP]
    regulation of female receptivity [IMP][NAS]
    peripheral nervous system development [TAS]
    somatic muscle development [TAS]
    Molecular Function: nucleic acid binding [IEA][NAS]
    DNA binding [TAS]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANVVNMNSL LNGKDSRWLQ LEVCREFQRN KCSRQDTECK FAHPPANVEV QNGKVTACYD  60
   61 SIKGRCNRDK PPCKYFHPPQ HLKDQLLING RNHLALKNAL MQQMGIAPGQ PVISGQVPAV 120
  121 ATNPYLTGIP ANSYSPYYTT GHLVPALLGP DPVTSQLGPV VPQTVQVAQQ KIPRSDRLET 180
  181 SPLAAHHHQQ QQQLQHQLNN INNNNNHSTA GAAATSTTAT TTTNNAAAAA AAAAAAAAAA 240
  241 VMGHHTLEVG KKRAADTTDM FPLVFFCSFP SPCVFAFLNC SIFGFLRLWF SLFNLRH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] PSI-BLAST 13.69897 No description for 2e5sA was found.
    2 View Details [105..212] MSA 4.144995 View MSA. No confident structure predictions are available.
    3 View Details [213..297] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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