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Protein Overview: gi|21645323, gi|...

General Information:
Name(s) found: gi|24653980 [NCBI NR]
gi|21645323 [NCBI NR]
Description(s) found:
Found 11 descriptions.
SHOW ALL
  • gi|24653980|ref|NP_725511.1| Stretchin-Mlck, isoform E [Drosophila melanogaster] [NCBI NR]
  • gi|21645323|gb|AAM70939.1| Stretchin-Mlck, isoform E [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 2403 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein amino acid phosphorylation [IEA][ISS][NAS]
    Molecular Function: ATP binding [IEA]
    calmodulin-dependent protein kinase activity [IDA]
    structural constituent of cytoskeleton [ISS]
    protein serine/threonine kinase activity [NAS]
    myosin light chain kinase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGETENGDIE PRASAEPEAA SAQDTLQVPT QKKRKLKSPT PGSLRGRSAT PIHGRSQTPF  60
   61 TLYMTRRSAT PSTWRSITPF LKREEKEKTP FELGRDIKSQ TTCNIAVFDR ALVMDISEPL 120
  121 DVQKPVRYIT SDLSVIDRAA VMDVSNVEVI YVVEEYEEVE EEEIIEEVKP KKKEKKARKP 180
  181 RAQRKSIDKD MSPSGAEDGD DLGDFGGDDR EDSVDLDDGD EPVKKGKKKA PPKKKEKKEK 240
  241 SPSPKLTLKL EIGGGQKASK KMFEQQQQQA KPPPKKSKMV LQMEEQAKAA AKAAEEAAAR 300
  301 AKPKGETFEE RQKRLQAEKE EQERLEAEQR AQEEAEAEAE AEAEEDEEDP SNVGEEGEEG 360
  361 TEAGYGDEDQ EQEYPEDEIE AEPEEDTKKK EKRRGSDSSD DFVRPDPHEE ERWQRIAAVE 420
  421 GEEFMQQMRK YSQAKRISEK ERDADWQRRR EQARNPKFIN FLSDRAVEAG QSVRLACAVD 480
  481 GPELSVKWYH NRKQLERDGC HRIINNNNIL VLEVLNTTIL DSGEYSCVIS NQNDETSSSC 540
  541 IVTIYEIFKD EPKPPSIQYI KEYYHLRDDE LTIECHVHGY PRPVITWWRG CFQVKPSYKF 600
  601 TMLEEAHGVC KLLIYKPGNK DGGIYTMKAI NSSGEVQINH TVEVARNLHY HVPGIFHARD 660
  661 KIQLDSLKQA KKAMEAALKS KADSDQRRAE AEEEQARLHP VKATPERLVP AKQKLAFATQ 720
  721 LRDRMALEGS TIKFVATVIG PDPNTRWMKD DKWVVVGGNI KNLSEEGKAI LEVGNVTSAD 780
  781 SGVYKCVAKN DLSEIETSCY FKVYAAQADG DESEPIFALP LRDVYHASQN DLILDTKVRG 840
  841 NPRPEISWTK DQIPVVLDDR VVQIEHLDGI CELIINKPTI NDNGIYVCTA KNKLGSQSTT 900
  901 HTVVVDTTHT SRRSSILSAI AMQEGGGGGE SADAKAKGKK KKKEDEPEGG DGGYERRSRM 960
  961 PDPSPKQMLY FTVNLSNRYV AEGSKVKLQA VIGGPQPMIK WLKDDQNVTY GPNIRNMNRD1020
 1021 SLAVLEFTNA KVEDSGTYSI VAQNESCKIT TSAMLHVYET KVNTDVQPVF IRSLKETYHL1080
 1081 NTNELILETA VRGQPTPAVQ WFKDSIEIQS GGRFQIIEHQ DGTCELIIDR PDNKDSGKYV1140
 1141 VKAESRAGKM EISHYVLFEG QSHHIAENIH GVFHADKSLL RPKEVEKPVE KKPAPAAEPE1200
 1201 SEAEDGKAKR RAKKEEDDGA SSAYATDYAS DTASLSSKRR EKNIAIHFST SMRDRVVAEG1260
 1261 SKVKISCFLE AKEPQVKWFK DGEQIQNSPK IRGRYSEGLC LLEVMSATAE DNGEYKCWGR1320
 1321 DETGEASTSC RLEVYENPGT GDVPPTFTRN IKDTMHGKIN ELQLDVHVRG LPTPAVTWVK1380
 1381 DGVKIENSDK YQQVDHDDGT CELFISRPKA SDSGKYVCQA ENREGKTEIV HMITVEPRVR1440
 1441 APRISPPREG RPPRPSGDEE PAAAGEEGAE GAADGEGGEK RRRKPKPDEE EQTSSRREVP1500
 1501 PPPDLRKRLY FRNFLSNRTV KSGSNVKWMV NIDGPEPTAK WFFGDQPIAF GPRSKMSMQD1560
 1561 GIAWLNLVGV TEEDAGEYTL RVRGSENEIV STCNLFVYST GKPEVIPPTF VVGIKDAYHS1620
 1621 QGNQLTLECK VSGSPKPHIY WQRDNTLLPI EGTKYQYEEQ SDGIKLLTIN NFGSNDSGLY1680
 1681 TCYAESENGQ MKISKFVQAS DYVRERIADK KPIDKVIQEI KRDESSSAAA NDTAAAKAKA1740
 1741 REAKLRLNLE TSLKTMTIGS GNKAQLICYV TGIIEDVHWL RNDERVTKDA RHKIYNINGA1800
 1801 ISLEIYDARV EDSGHYRCVV KNSRQTVESA GQLSVLDQST GKLPESFSSG IIESYDDQRN1860
 1861 EIVLSCQVIG RPSVSWMRDD HSICNNRYRT IEEPGGVRKL VIRNPISSDC GIFACYAEHE1920
 1921 DRIDSTSITI KAADLKRLIN VSQEEIPSIG DHESTPWSRS QSHLSSGSQV NGNGELHRAG1980
 1981 DRVLRNVGKG KPLFHTLLHD RTVSEGANLR LVCSVSGDEN THIEWLKNHK PLPRSDNRYQ2040
 2041 TVYLNGEASL EIFAAVADDS GNYTCCATND FGESLTHAQL RVYKNFKEAP LPSTFTQPIR2100
 2101 DTYSLNENEL VLDCRVRGQP RPEIQWIKGT EPIEASEKFK PSDQADGYAK LVIVNPTEKD2160
 2161 SGIYWCVARN EGAENKISHQ VDFKGRQHYS LEKTHGFFHR DPNKPHFLLP LGNQTVCNGG2220
 2221 TVAISAEFME TSTPIEVKWL RDRRVVDGPN VKALADRGVY TLTIMNAGPE VEGTYTCRAS2280
 2281 NAFGRIESNV NVDVAVGAEK DERPPLFLSR PDTEMKIAVG DPFSLSFRIA GDPKPKLTFM2340
 2341 KGTKDITQSD RVSKEVSDDY TRFSVQQAQI SDSGTYFVVA RNNFGTDRIF VTVTIKIPKK2400
 2401 KEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] FFAS03 1.09 No description for 2j63A was found.
    2 View Details [187..310] deduced N/A No confident structure predictions are available.
    3 View Details [311..443] deduced N/A No confident structure predictions are available.
    4 View Details [444..658] PSI-BLAST 14.045757 Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi
    5 View Details [659..1244] PSI-BLAST 55.522879 Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
    6 View Details [1245..1441] PSI-BLAST 42.0 Hemolin
    7 View Details [1442..1704] PSI-BLAST 29.045757 Fibroblast growth factor receptor, FGFR
    8 View Details [1705..1910] PSI-BLAST 58.0 Axonin-1
    9 View Details [1911..1980] FFAS03 1.01 No description for 2ch8A was found.
    10 View Details [1981..2256] PSI-BLAST 8.522879 The structure of an antitumor CH2-domain-deleted humanized antibody
    11 View Details [2257..2403] PSI-BLAST 37.69897 Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • telethonin binding
    		•  6.64811984458494 bayes_pls_golite062009
  • alpha-actinin binding
    		•  5.77350124471385 bayes_pls_golite062009
  • actinin binding
    		•  5.69539760434923 bayes_pls_golite062009
  • structural constituent of muscle
    		•  4.93896503565413 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • antigen binding
    		•  1.63189745559168 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.58610597245454 bayes_pls_golite062009
  • actin binding
    		•  1.42681407553255 bayes_pls_golite062009
  • protein kinase activity
    		•  1.36635494500222 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32330470851159 bayes_pls_golite062009
  • DNA binding
    		•  1.19412627500732 bayes_pls_golite062009
  • myosin light chain kinase activity
    		•  1.17845072849922 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16252234499274 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.02286631988334 bayes_pls_golite062009
  • kinase activity
    		•  0.929878054374821 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.878595022643164 bayes_pls_golite062009
  • actin filament binding
    		•  0.760856470721016 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.66378995104464 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.6127264879262 bayes_pls_golite062009
  • titin binding
    		•  0.599892148302011 bayes_pls_golite062009
  • structural molecule activity
    		•  0.567620977360967 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.564762108830441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.54549168007511 bayes_pls_golite062009
  • receptor activity
    		•  0.438456574760785 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.0963660533195985 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0579247757286607 bayes_pls_golite062009
  • transferase activity
    		•  0.053007146193305 bayes_pls_golite062009
    5 No functions predicted.
    6
    Term Confidence Notes
  • telethonin binding
    		•  6.64811984458494 bayes_pls_golite062009
  • alpha-actinin binding
    		•  5.77350124471385 bayes_pls_golite062009
  • actinin binding
    		•  5.69539760434923 bayes_pls_golite062009
  • structural constituent of muscle
    		•  4.93896503565413 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • antigen binding
    		•  1.63189745559168 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.58610597245454 bayes_pls_golite062009
  • actin binding
    		•  1.42681407553255 bayes_pls_golite062009
  • protein kinase activity
    		•  1.36635494500222 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32330470851159 bayes_pls_golite062009
  • DNA binding
    		•  1.19412627500732 bayes_pls_golite062009
  • myosin light chain kinase activity
    		•  1.17845072849922 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16252234499274 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.02286631988334 bayes_pls_golite062009
  • kinase activity
    		•  0.929878054374821 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.878595022643164 bayes_pls_golite062009
  • actin filament binding
    		•  0.760856470721016 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.66378995104464 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.6127264879262 bayes_pls_golite062009
  • titin binding
    		•  0.599892148302011 bayes_pls_golite062009
  • structural molecule activity
    		•  0.567620977360967 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.564762108830441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.54549168007511 bayes_pls_golite062009
  • receptor activity
    		•  0.438456574760785 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.0963660533195985 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0579247757286607 bayes_pls_golite062009
  • transferase activity
    		•  0.053007146193305 bayes_pls_golite062009
    7
    Term Confidence Notes
  • telethonin binding
    		•  6.64811984458494 bayes_pls_golite062009
  • alpha-actinin binding
    		•  5.77350124471385 bayes_pls_golite062009
  • actinin binding
    		•  5.69539760434923 bayes_pls_golite062009
  • structural constituent of muscle
    		•  4.93896503565413 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • antigen binding
    		•  1.63189745559168 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.58610597245454 bayes_pls_golite062009
  • actin binding
    		•  1.42681407553255 bayes_pls_golite062009
  • protein kinase activity
    		•  1.36635494500222 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32330470851159 bayes_pls_golite062009
  • DNA binding
    		•  1.19412627500732 bayes_pls_golite062009
  • myosin light chain kinase activity
    		•  1.17845072849922 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16252234499274 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.02286631988334 bayes_pls_golite062009
  • kinase activity
    		•  0.929878054374821 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.878595022643164 bayes_pls_golite062009
  • actin filament binding
    		•  0.760856470721016 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.66378995104464 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.6127264879262 bayes_pls_golite062009
  • titin binding
    		•  0.599892148302011 bayes_pls_golite062009
  • structural molecule activity
    		•  0.567620977360967 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.564762108830441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.54549168007511 bayes_pls_golite062009
  • receptor activity
    		•  0.438456574760785 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.0963660533195985 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0579247757286607 bayes_pls_golite062009
  • transferase activity
    		•  0.053007146193305 bayes_pls_golite062009
    8
    Term Confidence Notes
  • telethonin binding
    		•  6.64811984458494 bayes_pls_golite062009
  • alpha-actinin binding
    		•  5.77350124471385 bayes_pls_golite062009
  • actinin binding
    		•  5.69539760434923 bayes_pls_golite062009
  • structural constituent of muscle
    		•  4.93896503565413 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • antigen binding
    		•  1.63189745559168 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.58610597245454 bayes_pls_golite062009
  • actin binding
    		•  1.42681407553255 bayes_pls_golite062009
  • protein kinase activity
    		•  1.36635494500222 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32330470851159 bayes_pls_golite062009
  • DNA binding
    		•  1.19412627500732 bayes_pls_golite062009
  • myosin light chain kinase activity
    		•  1.17845072849922 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16252234499274 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.02286631988334 bayes_pls_golite062009
  • kinase activity
    		•  0.929878054374821 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.878595022643164 bayes_pls_golite062009
  • actin filament binding
    		•  0.760856470721016 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.66378995104464 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.6127264879262 bayes_pls_golite062009
  • titin binding
    		•  0.599892148302011 bayes_pls_golite062009
  • structural molecule activity
    		•  0.567620977360967 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.564762108830441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.54549168007511 bayes_pls_golite062009
  • receptor activity
    		•  0.438456574760785 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.0963660533195985 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0579247757286607 bayes_pls_golite062009
  • transferase activity
    		•  0.053007146193305 bayes_pls_golite062009
    9 No functions predicted.
    10
    Term Confidence Notes
  • telethonin binding
    		•  6.64811984458494 bayes_pls_golite062009
  • alpha-actinin binding
    		•  5.77350124471385 bayes_pls_golite062009
  • actinin binding
    		•  5.69539760434923 bayes_pls_golite062009
  • structural constituent of muscle
    		•  4.93896503565413 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • antigen binding
    		•  1.63189745559168 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.58610597245454 bayes_pls_golite062009
  • actin binding
    		•  1.42681407553255 bayes_pls_golite062009
  • protein kinase activity
    		•  1.36635494500222 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32330470851159 bayes_pls_golite062009
  • DNA binding
    		•  1.19412627500732 bayes_pls_golite062009
  • myosin light chain kinase activity
    		•  1.17845072849922 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16252234499274 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.02286631988334 bayes_pls_golite062009
  • kinase activity
    		•  0.929878054374821 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.878595022643164 bayes_pls_golite062009
  • actin filament binding
    		•  0.760856470721016 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.66378995104464 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.6127264879262 bayes_pls_golite062009
  • titin binding
    		•  0.599892148302011 bayes_pls_golite062009
  • structural molecule activity
    		•  0.567620977360967 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.564762108830441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.54549168007511 bayes_pls_golite062009
  • receptor activity
    		•  0.438456574760785 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.0963660533195985 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0579247757286607 bayes_pls_golite062009
  • transferase activity
    		•  0.053007146193305 bayes_pls_golite062009
    11
    Term Confidence Notes
  • telethonin binding
    		•  6.64811984458494 bayes_pls_golite062009
  • alpha-actinin binding
    		•  5.77350124471385 bayes_pls_golite062009
  • actinin binding
    		•  5.69539760434923 bayes_pls_golite062009
  • structural constituent of muscle
    		•  4.93896503565413 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • antigen binding
    		•  1.63189745559168 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.58610597245454 bayes_pls_golite062009
  • actin binding
    		•  1.42681407553255 bayes_pls_golite062009
  • protein kinase activity
    		•  1.36635494500222 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32330470851159 bayes_pls_golite062009
  • DNA binding
    		•  1.19412627500732 bayes_pls_golite062009
  • myosin light chain kinase activity
    		•  1.17845072849922 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16252234499274 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.02286631988334 bayes_pls_golite062009
  • kinase activity
    		•  0.929878054374821 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.878595022643164 bayes_pls_golite062009
  • actin filament binding
    		•  0.760856470721016 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.66378995104464 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.6127264879262 bayes_pls_golite062009
  • titin binding
    		•  0.599892148302011 bayes_pls_golite062009
  • structural molecule activity
    		•  0.567620977360967 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.564762108830441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.54549168007511 bayes_pls_golite062009
  • receptor activity
    		•  0.438456574760785 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.0963660533195985 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0579247757286607 bayes_pls_golite062009
  • transferase activity
    		•  0.053007146193305 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle