Protein Overview: kn-PB

General Information:
Name(s) found:	kn-PB / FBpp0111721 [FlyBase]
Description(s) found: Found 20 descriptions. SHOW ALL	The gene knot is referred to in FlyBase by the symbol Dmel\kn (CG10197, FBgn0001319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10660152..10694566. It has the cytological map location 51C2-51C3. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: innate immune response; response to symbiont; regulation of transcription, DNA-dependent; specification of segmental identity, intercalary segment; head segmentation; regulation of lamellocyte differentiation; embryonic development via the syncytial blastoderm; imaginal disc-derived wing vein specification. 22 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: organ system; adult segment; hypodermal muscle of larval abdomen; adult mesothoracic segment; abdominal oblique muscle; thoracic segment; cephalopharyngeal skeleton; wing cell; larval abdominal segment; larval abdominal segment 5. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	575 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA][NAS]
Biological Process:	head segmentation [IMP] anterior head segmentation [TAS] posterior head segmentation [TAS] blastoderm segmentation [TAS] imaginal disc-derived wing morphogenesis [TAS] regulation of transcription, DNA-dependent [IEA][IMP] pattern specification process [TAS] specification of segmental identity, intercalary segment [IMP] imaginal disc-derived wing vein specification [IMP] regulation of transcription [IEA][TAS] response to symbiont [IMP] embryonic development via the syncytial blastoderm [IMP] innate immune response [IMP] regulation of lamellocyte differentiation [IMP]
Molecular Function:	DNA binding [IEA] transcription regulator activity [IEA][TAS] specific RNA polymerase II transcription factor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEWGRKLYPS AVSGPRSAGG LMFGLPPTAA VDMNQPRGPM TSLKEEPLGS RWAMQPVVDQ  60
   61 SNLGIGRAHF EKQPPSNLRK SNFFHFVIAL YDRAGQPIEI ERTAFIGFIE KDSESDATKT 120
  121 NNGIQYRLQL LYANGARQEQ DIFVRLIDSV TKQAIIYEGQ DKNPEMCRVL LTHEVMCSRC 180
  181 CDKKSCGNRN ETPSDPVIID RFFLKFFLKC NQNCLKNAGN PRDMRRFQVV ISTQVAVDGP 240
  241 LLAISDNMFV HNNSKHGRRA KRLDTTEGTG NTSLSISGHP LAPDSTYDGL YPPLPVATPC 300
  301 IKAISPSEGW TTGGATVIIV GDNFFDGLQV VFGTMLVWSE LITSHAIRVQ TPPRHIPGVV 360
  361 EVTLSYKSKQ FCKGSPGRFV YVSALNEPTI DYGFQRLQKL IPRHPGDPEK LQKEIILKRA 420
  421 ADLVEALYSM PRSPGGSTGF NSYAGQLAVS VQDGSGQWTE DDYQRAQSSS VSPRGGYCSS 480
  481 ASTPHSSGGS YGATAASAAV AATANGYAPA PNMGTLSSSP GSVFNSTSMS AVSSTWHQAF 540
  541 VQHHHAATAH PHHHYPHPHQ PWHNPAVSAA TAAAV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: kn-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: