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Protein Overview: CG8394-PA

General Information:
Name(s) found: CG8394-PA / FBpp0086703 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8394 (CG8394, FBgn0033911). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10086505..10088226. It has the cytological map location 50E4. Based on sequence similarity, it is predicted to have molecular function</span>: amino acid transmembrane transporter activity; gamma-aminobutyric acid:hydrogen symporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: amino acid transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 549 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: amino acid transport [ISS]
    Molecular Function: gamma-aminobutyric acid:hydrogen symporter activity [ISS]
    amino acid transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFIAKLKAT PLPPLRNILN VAVQTARQQI PERKDYEQPP GSTAQQHHHS QQAQHKAMEA  60
   61 GMDGGDTTEM SSNPFRNAGS WTNDGEGGGD GDGEYRNEYQ STSFNEYDGR YQQTDGFRQG 120
  121 SIASEGSSFV CEGEGGGGCK IDEFQAAWNV TNAIQGMFIV SLPFAVLHGG YWAIVAMVGI 180
  181 AHICCYTGKV LVQCLYEPDP ATGQMVRVRD SYVAIAKVCF GPKLGARAVS IAQLIELLMT 240
  241 CILYVVVCGD LLAGTYPQGS FDSRSWMLFV GIFLLPMGFL KSLKMVSTLS FWCTMSHIVI 300
  301 NAVILGYCLL QIGDWGWSKV RFSIDMENFP ISLGVIVFSY TSQIFLPTLE GNMIDRSKFN 360
  361 WMLDWSHIAA AVFKAGFGYI CFLTFQNDTQ QVITNNLHSQ GFKGMVNFFL VIKALLSYPL 420
  421 PYYAACELLE RNFFRGPPKT KFPTIWNLDG ELKVWGLGFR VGVIVSTILM AIFIPHFSIL 480
  481 MGFIGSFTGT MLSFIWPCYF HIKIKGHLLD QKEIAKDYLI IGLGVLFGVI GIYDSGNALI 540
  541 NAFEIGLPF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] FFAS03 1.18 TUBULIN-PODOPHYLLOTOXIN: STATHMIN-LIKE DOMAIN COMPLEX
    2 View Details [135..549] FFAS03 1.64 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.765787959568968 bayes_pls_golite062009
  • protein binding
    		•  0.629439947822407 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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