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Protein Overview: CG6197-PA

General Information:
Name(s) found: CG6197-PA / FBpp0086749 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6197 (CG6197, FBgn0033859). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9481154..9484068. It has the cytological map location 50B4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: regulation of alternative nuclear mRNA splicing, via spliceosome; phagocytosis, engulfment. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 883 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    Biological Process: phagocytosis, engulfment [IMP]
    regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTKTIKSLN LEINFEVEDV PYEEEILRNA YSVKHWLRYI DHKAKAPNNG VNMVYERALK  60
   61 ELPGSYKIWH NYLRTRRKQV RGKIPTDPMY EEVNSAFERA LVFMHKMPRI WMDYGAFMTS 120
  121 QCKITRTRHV FDRALRALPI TQHGRIWPLY LQFVRRFEMP ETALRVYRRY LKLFPEDTEE 180
  181 YVDYLQEADR LDEAAQQLAH IVDNEHFVSK HGKSNHQLWN ELCDLISKNP HKVHSLNVDA 240
  241 IIRGGLRRYT DQLGHLWNSL ADYYVRSGLF DRARDIYEEA IQTVTTVRDF TQVFDEYAQF 300
  301 EELSLNRRME QVAANEAATE EDDIDVELRL SRFEYLMERR LLLLNSVLLR QNPHNVHEWH 360
  361 KRVTLYEDKP AEIISTYTEA VQTVQPKQAV GKLHTLWVEF AKFYEANGQV EDARVVFERG 420
  421 TEVEYVKVED LAAVWCEWAE MELRQQQFEA ALKLMQRATA MPKRKIAYYD DTETVQARLH 480
  481 RSLKVWSMYA DLEESFGTFK TCKAVYERII DLKICTPQII INYGMFLEEH NYFEEAYRAY 540
  541 EKGISLFKWP NVYDIWNSYL TKFLERYGGT KLERARDLFE QCLDQCPPEH AKYFYLLYAK 600
  601 LEEEHGLARH AMSVYDRATS AVKEDEMFDM YNIFIKKAAE IYGLPRTREI YEKAIESLPE 660
  661 QNMRHMCVKF AELETKLGEV DRARAIYAHC SQVCDPRITA DFWQTWKEFE VRHGNEDTMR 720
  721 EMLRIKRSVQ ATYNTQVNMM AAQFLSTNNG AAADAGAGAG PDAMRLLEEK ARQAAAESKQ 780
  781 KPIEKAASNI MFVRGETQGG AKDKKDTVVN PDEIDIGDSD EDDEEEDDDE ENEMTNENQA 840
  841 SAAVTKTDEE GLVMKKLRFE QKAIPAKVFG SLKPSNQGDS DGE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] PSI-BLAST 18.522879 Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
    2 View Details [74..572] PSI-BLAST 22.30103 No description for 2gw1A was found.
    3 View Details [573..774] PSI-BLAST 6.30103 Helicobacter cysteine rich protein C (HcpC)
    4 View Details [775..883] PSI-BLAST 43.09691 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.96958278583621 bayes_pls_golite062009
  • protein binding
    		•  0.559882636047776 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle