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Protein Overview: Prp38-PA

General Information:
Name(s) found: Prp38-PA / FBpp0087663 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene pre-mRNA processing factor 38 is referred to in FlyBase by the symbol Dmel\Prp38 (CG30342, FBgn0050342). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5031464..5032656. It has the cytological map location 45A12. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: nuclear mRNA splicing, via spliceosome; regulation of G2/M transition of mitotic cell cycle. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 330 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    protein complex [IPI]
    Biological Process: regulation of G2/M transition of mitotic cell cycle [IMP]
    nuclear mRNA splicing, via spliceosome [IC][IMP]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANRTVKEAK NVHGTNPQYL IEKIIRSRIY DSKYWKEQCF ALTAELLVDK AMELRFVGGV  60
   61 YGGNIKPTQF LCLTLKMLQI QPEKDIVVEF IKNEEFKYVR ALGAFYLRLT GAALDCYKYL 120
  121 EPLYIDNRKL RRQNRAGQFE IVYMDEYIDE LLRNDRVCDI ILPRIQKRSI LEENNEIEPK 180
  181 VSVLDEDLDD ELPSDEEKAD ETNRPKENST AVRRPRRVRS KSRSRSRERE RRSGQGNSAR 240
  241 SRDYYDELED YDRQRNRVRN RDTHNEDYDR RQNNGRHDRE RERQDRDSIR ERERDGDRDR 300
  301 RDRERERERD RGRHDQRERD SRGERDRRRY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] Pfam 80.113509 No description for PF03371.6 was found. No confident structure predictions are available.
    2 View Details [203..330] MSA 14.131997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle