YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: alc-PA

General Information:
Name(s) found: alc-PA / FBpp0087705 [FlyBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • The gene alicorn is referred to in FlyBase by the symbol Dmel\alc (CG8057, FBgn0260972). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5022880..5025455. It has the cytological map location 45A11-45B1. Based on sequence similarity, it is predicted to have molecular function</span>: AMP-activated protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus; neuron homeostasis; maintenance of apical/basal cell polarity. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 341 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: neuron homeostasis [IMP]
    response to DNA damage stimulus [IMP]
    maintenance of apical/basal cell polarity [IMP]
    Molecular Function: AMP-activated protein kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNASSSVHM QRERHKSTDL STPSSPAHFR DSIGGGGAGQ GGSAGAAALG AAAGAVGAAG  60
   61 GGGGGGGGQA FSFDKKHTAV LNEGSSQEDD DPYYTGTGTG STRRGTAHDD ATSAVTRDHS 120
  121 SMDNNEEEEE AAVGAEPATG SQLTGDEDDI RKTALPTVLR WDGGGKNVTI SGTFSDWKPM 180
  181 AMVRSHQNFV TIIDLPEGDH QYKFCVDGEW KHDPKLKSVE NAEGQRNNLV SVRESDFEVF 240
  241 QALAKDSENV TNYAEKEYSQ EVPQVKPWEK VSGPPVLPPH LLQVILNKDT PLSCEPTLLP 300
  301 EPNHVMLNHL YALSIKDGVM VLSATHRYRK KYVTTLLYKP I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] MSA 4.146997 View MSA. No confident structure predictions are available.
    2 View Details [136..247] PSI-BLAST 31.221849 the glycogen-binding domain of the AMP-activated protein kinase
    3 View Details [248..341] PSI-BLAST 35.0 No description for 2v8qB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.46

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle