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Protein Overview: CG8791-PA

General Information:
Name(s) found: CG8791-PA / FBpp0087925 [FlyBase]
Description(s) found:
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  • gi|28573299|ref|NP_610332.3| CG8791 [Drosophila melanogaster] [NCBI NR]
  • gi|28381076|gb|AAF59171.3| CG8791 [Drosophila melanogaster] [NCBI NR]
  • gi|21430484|gb|AAM50920.1| LP07366p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8791 (CG8791, FBgn0033234). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3814182..3817432. It has the cytological map location 43F2. Based on sequence similarity, it is predicted to have molecular function</span>: high affinity inorganic phosphate:sodium symporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8791-PA translation from_gene[CG8791 CG8791 FBgn0033234] seq_release:3 mol_weight=51724 cds_boundaries:(2R:2,987,648..2,990,508[+]) aa_length:477 transcript_info:[CG8791-RA seq_release:3] gene_info:[gene symbol:CG8791 FBgn0033234 gene_boundaries:(2R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8MS66) LP07366p (CG8791-PA) [DrosMelano7227.FASTAC.txt]
  • CG8791-PA [Drosophila melanogaster]gi|21430484|gb|AAM50920.1| LP07366p [Drosophila melanogaster]gi|28573299|ref|NP_610332.3| CG8791-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(3814252..3814285,3815591..3815800,3815864..3816318,3816381..3817115); ID=FBpp0087925; name=CG8791-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610 [fly-100309-contam.fasta]
  • CG8791-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LP07366p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(3814252..3814285,3815591..3815800,3815864..3816318,3816381..3817115); ID=FBpp0087925; name=CG8791-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610332,GB_protein:AAF59171; MD5=585ba439613c97b6e475d96dd352aa9f; length=477; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(3814252..3814285,3815591..3815800,3815864..3816318,3816381..3817115); ID=FBpp0087925; name=CG8791-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610332,GB_protein:AAF59171; MD5=585ba439613c97b6e475d96dd352aa9f; length=477; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG8791 OS=Drosophila melanogaster GN=CG8791 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(3814252..3814285,3815591..3815800,3815864..3816318,3816381..3817115); ID=FBpp0087925; name=CG8791-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610332,GB_protein:AAF59171,FlyMine:FBpp0087925,modMine:FBpp0087925; MD5=585ba439613c97b6e475d96dd352aa9f; length=477; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(7926747..7926780,7928086..7928295,7928359..7928813,7928876..7929610); ID=FBpp0087925; name=CG8791-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610332,GB_protein:AAF59171,FlyMine:FBpp0087925,modMine:FBpp0087925; MD5=585ba439613c97b6e475d96dd352aa9f; length=477; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(7926747..7926780,7928086..7928295,7928359..7928813,7928876..7929610); ID=FBpp0087925; name=MFS12-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610332,GB_protein:AAF59171,FlyMine:FBpp0087925,modMine:FBpp0087925; MD5=585ba439613c97b6e475d96dd352aa9f; length=477; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • CG8791, isoform A OS=Drosophila melanogaster GN=MFS12 PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0087925 type=protein; loc=2R:join(7926747..7926780,7928086..7928295,7928359..7928813,7928876..7929610); ID=FBpp0087925; name=MFS12-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610332,GB_protein:AAF59171,FlyMine:FBpp0087925,modMine:FBpp0087925; MD5=585ba439613c97b6e475d96dd352aa9f; length=477; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(7926747..7926780,7928086..7928295,7928359..7928813,7928876..7929610); ID=FBpp0087925; name=MFS12-PA; parent=FBgn0033234,FBtr0088849; dbxref=FlyBase:FBpp0087925,FlyBase_Annotation_IDs:CG8791-PA,GB_protein:AAF59171.3,REFSEQ:NP_610332,GB_protein:AAF59171,UniProt/TrEMBL:Q8MS66,FlyMine:FBpp0087925,modMine:FBpp0087925; MD5=585ba439613c97b6e475d96dd352aa9f; length=477; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 477 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: transmembrane transport [IEA]
    Molecular Function: high affinity inorganic phosphate:sodium symporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFEPSEDKA RPGGLGVRHW QAVLLFVGMM INYFQRVNIS AAIVPMTQST AGAPFYTWDT  60
   61 SDKSLILSSF FWGYVVSQVP AGLLAKRFGA KLVLGLATAI GGILCFFHPI AAKSGWQSIC 120
  121 VLRVLTGLVQ GTVYPCVHTL LAKWVPRTER GLLTTGVYSG AQFGTAVILV TSGFIFESSM 180
  181 GWPGLFYLSG GLSLAWALLF FWQAANEPVT ASRISKGEVE YIESLTGSNS SSQSMPVPWM 240
  241 SIFRSPAFYG LLAAHCGFTW GFYTLLTEMP TYMSMVLQLN VKSNAFLSSL PYFAMGLLCF 300
  301 VVSPISDLLI NRGTISITTA RKLFNSIGQW GPMACLIGLG YMTADEKTWA ILLLTLAVGI 360
  361 NAGCSCGYLI NHIDLSPNFA GPMMGVTNGI AGVTSIIAPL VVGAIVSDEE DPSQWRMVFF 420
  421 ITGGIYLVCN TIFVIFGKAT IQIWNEPPST SSTMTLRSHQ ENDSKSIVPT SDKDIRY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..477] PSI-BLAST 41.154902 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.78662033436109 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.02928844080554 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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