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Protein Overview: phr-PB

General Information:
Name(s) found: phr-PB / FBpp0087915 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene photorepair is referred to in FlyBase by the symbol Dmel\phr (CG11205, FBgn0003082). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3712997..3714824. It has the cytological map location 43E18. Based on sequence similarity, it is predicted to have molecular function</span>: deoxyribodipyrimidine photo-lyase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: DNA repair. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 535 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA repair [ISS]
    Molecular Function: deoxyribodipyrimidine photo-lyase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRTKAQKAG PSKKAAKNEK ASSEPKSDQE SSDEEASTSK ALLVSKPDYQ NFEQFLTHLE  60
   61 HQRVCTAANI QEFSFRKKRV RVLSKTEDVK ESSLGGVVYW MSRDGRVQDN WALLFAQRLA 120
  121 LKLELPLTVV FCLVPKFLNA TIRHYKFMMG GLQEVEQQCR ALDIPFHLLM GSAVEKLPQF 180
  181 VKSKDIGAVV CDFAPLRLPR QWVEDVGKAL PKSVPLVQVD AHNVVPLWVA SDKQEYAART 240
  241 IRNKINSKLG EYLSVFPPVV RHPHGTGCKN VNTVDWSAAY ASLQCDMEVD EVQWAKPGYK 300
  301 AACQQLYEFC SRRLRHFNDK RNDPTADALS GLSPWLHFGH ISAQRCALEV QRFRGQHKAS 360
  361 ADAFCEEAIV RRELADNFCF YNEHYDSLKG LSSWAYQTLD AHRKDKRDPC YSLEELEKSL 420
  421 TYDDLWNSAQ LQLVREGKMH GFLRMYWAKK ILEWTATPEH ALEYAILLND KYSLDGRDPN 480
  481 GYVGCMWSIG GVHDMGWKER AIFGKVRYMN YQGCRRKFDV NAFVMRYGGK VHKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] deduced N/A No confident structure predictions are available.
    2 View Details [95..535] PSI-BLAST 98.0 C-terminal domain of DNA photolyase; DNA photolyase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA photolyase activity
    		•  2.69544443093614 bayes_pls_golite062009
  • deoxyribodipyrimidine photo-lyase activity
    		•  2.01343813518186 bayes_pls_golite062009
  • binding
    		•  0.638180097229557 bayes_pls_golite062009
  • catalytic activity
    		•  0.609980967042895 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.168445004685844 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.143448587511534 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle