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View Structure Prediction Details

Protein: phr-PB
Organism: Drosophila melanogaster
Length: 535 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for phr-PB.

Description E-value Query
Range
Subject
Range
gi|1401030, gi|1... - gi|1401030|dbj|BAA05042.1| photolyase [Drosophila melanogaster], pir||S52047 deoxyribodipyrimidine p...
466.0 [0..1] [535..106]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRTKAQKAG PSKKAAKNEK ASSEPKSDQE SSDEEASTSK ALLVSKPDYQ NFEQFLTHLE  60
   61 HQRVCTAANI QEFSFRKKRV RVLSKTEDVK ESSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [95-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGVVYWMSRD GRVQDNWALL FAQRLALKLE LPLTVVFCLV PKFLNATIRH YKFMMGGLQE  60
   61 VEQQCRALDI PFHLLMGSAV EKLPQFVKSK DIGAVVCDFA PLRLPRQWVE DVGKALPKSV 120
  121 PLVQVDAHNV VPLWVASDKQ EYAARTIRNK INSKLGEYLS VFPPVVRHPH GTGCKNVNTV 180
  181 DWSAAYASLQ CDMEVDEVQW AKPGYKAACQ QLYEFCSRRL RHFNDKRNDP TADALSGLSP 240
  241 WLHFGHISAQ RCALEVQRFR GQHKASADAF CEEAIVRREL ADNFCFYNEH YDSLKGLSSW 300
  301 AYQTLDAHRK DKRDPCYSLE ELEKSLTYDD LWNSAQLQLV REGKMHGFLR MYWAKKILEW 360
  361 TATPEHALEY AILLNDKYSL DGRDPNGYVG CMWSIGGVHD MGWKERAIFG KVRYMNYQGC 420
  421 RRKFDVNAFV MRYGGKVHKK K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.0
Match: 1dnpA
Description: C-terminal domain of DNA photolyase; DNA photolyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA photolyase activity 2.69544443093614 bayes_pls_golite062009
deoxyribodipyrimidine photo-lyase activity 2.01343813518186 bayes_pls_golite062009
binding 0.638180097229557 bayes_pls_golite062009
catalytic activity 0.609980967042895 bayes_pls_golite062009
transcription regulator activity 0.168445004685844 bayes_pls_golite062009
transcription repressor activity 0.143448587511534 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle