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Protein Overview: Inos-PA

General Information:
Name(s) found: Inos-PA / FBpp0088368 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene Inos is referred to in FlyBase by the symbol Dmel\Inos (CG11143, FBgn0025885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3342419..3346368. It has the cytological map location 43C3. There is experimental evidence that it has the molecular function</span>: inositol-3-phosphate synthase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: inositol biosynthetic process. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 565 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS]
    Biological Process: inositol biosynthetic process [ISS]
    phospholipid biosynthetic process [IEA]
    Molecular Function: inositol-3-phosphate synthase activity [IDA][ISS][NAS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPTNNSTLE VISPKVQVDD EFITTDYDYQ TSHVKRTADG QLQVHPQTTS LKIRTGRHVP  60
   61 KLGVMLVGWG GNNGSTLTAA LEANRRQLKW RKRTGVQEAN WYGSITQAST VFIGSDEDGG 120
  121 DVYVPMKELL PMVEPDNIIV DGWDISGLHL GDAMRRAEVL DVALQDQIYD QLAQLRPRPS 180
  181 IYDPDFIAAN QSDRADNVIR GTRLEQYEQI RKDIRDFRER SGVDSVIVLW TANTERFADV 240
  241 QPGLNTTSQE LIASLEANHS EVSPSTIFAM ASIAEGCTYI NGSPQNTFVP GLIQLAEEKN 300
  301 VFIAGDDFKS GQTKIKSVLV DFLVGAGIKP VSIASYNHLG NNDGKNLSAP QQFRSKEISK 360
  361 SNVVDDMVAS NRLLYGPDEH PDHVVVIKYV PYVGDSKRAM DEYTSEIMMG GHNTLVIHNT 420
  421 CEDSLLATPL ILDLVILGEL STRIQLRNAE KESAPWVPFK PVLSLLSYLC KAPLVPQGSQ 480
  481 VVNSLFRQRA AIENILRGCI GLPPISHMTL EQRFDFSTIT NEPPLKRVKI LGQPCSVESV 540
  541 TNGKKLHANG HSNGSAKLAT NGNGH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..565] PSI-BLAST 1000.0 Myo-inositol 1-phosphate synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • inositol-3-phosphate synthase activity
    		•  5.14101880075866 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase activity
    		•  4.83517188189564 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
    		•  4.46099072756569 bayes_pls_golite062009
  • intramolecular lyase activity
    		•  3.61355415766141 bayes_pls_golite062009
  • catalytic activity
    		•  2.54843319568228 bayes_pls_golite062009
  • glucose-6-phosphate dehydrogenase activity
    		•  1.31087146124678 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.503001902398942 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.461954393123963 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.38381420992976 bayes_pls_golite062009
  • binding
    		•  0.382774999529641 bayes_pls_golite062009
  • 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
    		•  0.375786741986945 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  0.0028371262047614 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle