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Protein Overview: FBpp0307849, CG1...

General Information:
Name(s) found: FBpp0307849 [FlyBase]
CG11107-PA / FBpp0088040 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=2R:join(3275033..3275085,3275140..3275933,3276213..3276686,3276752..3277015,3277583..3277705,3277773..3278126,3278185..3278312); ID=FBpp0307849; name=CG11107-PB; parent=FBgn0033160,FBtr0336909; dbxref=REFSEQ:NP_001260766,GB_protein:AGB93299,FlyBase:FBpp0307849,FlyBase_Annotation_IDs:CG11107-PB; MD5=b1505c072857fdae5e3c1d96813f4446; length=729; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG11107 (CG11107, FBgn0033160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3274719..3278529. It has the cytological map location 43B2. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent helicase activity; ATP-dependent RNA helicase activity; RNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 729 amino acids

    Gene Ontology:
    Cellular Component: catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    spliceosomal complex [ISS]
    Biological Process: nuclear mRNA splicing, via spliceosome [IC][ISS]
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    RNA helicase activity [ISS]
    ATP-dependent helicase activity [ISS]
    ATP-dependent RNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRRIEVGE TYGSKAKKDP EASSSSAAAA AGTVAQILGG FVPNKQPPTM NPLTNTPYSQ  60
   61 RYQNLYKKRI ALPVFEYQAD FMRLLSLHQC IVLVGETGSG KTTQIPQWCV DFAVSKGRKG 120
  121 VSCTQPRRVA AMSVAQRVSE EMDVKLGEEV GYSIRFEDCS TAKTLLKYMT DGMLLREAMS 180
  181 DPMLDQYQVI LLDEAHERTL ATDILMGVLK EVIRQRSDLK LVVMSATLDA GKFQQYFDNA 240
  241 PLMKVPGRTH PVEIFYTPEP ERDYLEAAIR TVIQIHMCEE IEGDILMFLT GQEEIEEACK 300
  301 RIKREIDNLG SEIGELKCIP LYSTLPPNLQ QRIFEPAPPP NANGAIGRKV VVSTNIAETS 360
  361 LTIDGVVFVI DPGFAKQKVY NPRIRVESLL VSPISKASAQ QRSGRAGRTR PGKCFRLYTE 420
  421 KAFKNEMQDN TYPEILRSNL GTVVLQLKKL GIDDLVHFDF MDPPAPETLM RALELLNYLA 480
  481 ALDDDGNLTD LGAVMSEFPL DPQLAKMLIA SCQHNCSNEI LSITAMLSVP QCFVRPNEAK 540
  541 KAADEAKMRF AHIDGDHLTL LNVYHAFKQS SEDPNWCYEN FINFRSLKSA DNVRQQLARI 600
  601 MDRFNLRRTS TEFTSKDYYV NIRKALVQGF FMQVAHLERT GYYLTIKDNQ NVQLHPSTCL 660
  661 DHKPDWVIYN EFVLTTKNYI RTVTDVKPEW LCCLAPQYYD LNNFPQCEAK RQLELLQQRL 720
  721 ETKQYQKGF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..71] PSI-BLAST 69.0 No description for 2hyiC was found.
    2 View Details [72..580] PSI-BLAST 24.39794 No description for 2qeqA was found.
    3 View Details [581..729] Pfam 25.79588 No description for PF07717.7 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle