YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: pk-PC

General Information:
Name(s) found: pk-PC / FBpp0088115 [FlyBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • The gene prickle is referred to in FlyBase by the symbol Dmel\pk (CG11084, FBgn0003090). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3038207..3110885. It has the cytological map location 42F3-43A1. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: establishment or maintenance of cell polarity; establishment of ommatidial polarity; morphogenesis of a polarized epithelium. 99 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; appendage segment; adult mesothoracic segment; organ system; metatarsus; thoracic segment; external compound sense organ; peripheral nervous system; nervous system; wing hair. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1299 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [TAS]
    membrane [NAS]
    Biological Process: establishment of protein localization [TAS]
    maintenance of protein location [TAS]
    establishment or maintenance of cell polarity [IMP][NAS]
    establishment of planar polarity [TAS]
    protein localization [TAS]
    establishment of imaginal disc-derived wing hair orientation [TAS]
    establishment of ommatidial planar polarity [IMP]
    morphogenesis of a polarized epithelium [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSTGGGA GGSSGGPGGA DAAAAPAAGQ ATVTATGNME PAMVPRTANL LACKQWWRVC  60
   61 FLYGDQQKYY RQLYSKAAAQ RLADANQEPD NARDREYDTV DCDLIAGQLD AVEDADDGID 120
  121 LGDHSSTPKG GATTAGRPLF PHSSSPRRSK KLLRSLRAHV RGEKLPKNDT TTANESSEVT 180
  181 QRNARVTVLD DPFLFGIDAD HLGDLVVRGK RYSTLDATEN MARFYAEQEA TAQVLEIIEQ 240
  241 EEESPEQEAP KPALPPKQKQ QRPVPPLPPP PANRVTQDQG TQPAAPQVPL QPLTAGDLQF 300
  301 LNLSLRQRSL PRSMKPFKDA HDISFTFNEL DTSAEPEVAT GAAQQESNEP ISRTPLTQIS 360
  361 YLQKIPTLPR HFSPSGQGLA TPPALGSGGM GLPSSSSASA LYAAQAAAGI LPTSPLPLQR 420
  421 HQQYLPPHHQ QHPGAGMGPG PGSGAAAGPP LGPQYSPGCS ANPKYSNAQL PPPPHHHHQL 480
  481 SPALSTPSPP SLLHHPAGGT SSASAHAPFL GGPHMDMQRQ SHSDDDSGCA LEEYTWVPPG 540
  541 LRPDQVRLYF SQIPDDKVPY VNSPGEQYRV RQLLHQLPPH DNEVRYCHSL TDEERKELRL 600
  601 FSTQRKRDAL GRGNVRQLMS ARPCDGCDDL ISTGDIAVFA TRLGPNASWH PACFACSVCR 660
  661 ELLVDLIYFH RDGRMYCGRH HAETLKPRCS ACDEIILADE CTEAEGRAWH MNHFACHECD 720
  721 KQLGGQRYIM REGKPYCLHC FDAMFAEYCD YCGEAIGVDQ GQMSHDGQHW HATDECFSCN 780
  781 TCRCSLLGRA FLPRRGAIYC SIACSKGEPP TPSDSSGTGM YTTPTPPTQR VRPHPQAPLP 840
  841 ARIPSSHASS SPPMSPQQQQ QHQATFNQAM YQMQSQQMEA AGGLVDQSKS YAASDSDAGV 900
  901 VKDLEHGGHM GGGDLTDFSG GRASSTSQNL SPLNSPGDFQ PHFLPKPMEL QRDGVYNFNE 960
  961 MSSNLDAAWS AKPTNSYHLQ RQLLENPHTA SMPELAGKLV APPAHMQHLS QLHAVSSHQF1020
 1021 QQHEYADILH PPPPPPGEIP ELPTPNLSVA STALPPELMG SPTHSAGDRS LNTPMSTQSA1080
 1081 SHAPPHPVSI LSGASSSSPM SGEPAKKKGV RFEGIPDTLP RSRSYSGNGA GTSGGGERER1140
 1141 DRDKDKEGGG RHGHGHSSRR RRRRKSSSSS SHHRSGSGHR SHSTTRADTY APAQPLSSSY1200
 1201 QGPPSVLQAA NLVHESPSRQ QRERERERER EESEESDVCS TCSSSSSSSE DYMMMYQLPQ1260
 1261 RRHYGGVRVS YVPNDALAYD RKRKPSELGG DKDKNCIIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210] deduced N/A No confident structure predictions are available.
    2 View Details [211..400] MSA 2.077996 View MSA. No confident structure predictions are available.
    3 View Details [401..480] deduced N/A No confident structure predictions are available.
    4 View Details [481..558] PSI-BLAST 20.30103 Transcription factor IIIA, TFIIIA
    5 View Details [559..746] PSI-BLAST 46.0 No description for 2i13A was found.
    6 View Details [747..826] FFAS03 2.7 Solution structure of the Skeletal muscle LIM-protein 1
    7 View Details [827..975] PSI-BLAST 18.154902 Ying-yang 1 (yy1, zinc finger domain)
    8 View Details [976..1087] deduced N/A No confident structure predictions are available.
    9 View Details [1088..1299] MSA 1.124985 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.26906680202757 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.5361877165154 bayes_pls_golite062009
  • DNA binding
    		•  1.50805568602414 bayes_pls_golite062009
  • protein binding
    		•  0.905022998164426 bayes_pls_golite062009
  • transcription factor activity
    		•  0.594688838246446 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
    5 No functions predicted.
    6
    Term Confidence Notes
  • binding
    		•  2.0300494058962 bayes_pls_golite062009
  • protein binding
    		•  1.20339329058617 bayes_pls_golite062009
  • receptor activity
    		•  1.00000843633623 bayes_pls_golite062009
  • transporter activity
    		•  0.893102092384062 bayes_pls_golite062009
  • signal transducer activity
    		•  0.73994900849782 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.73994900849782 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.7072042577999 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.489535882040485 bayes_pls_golite062009
  • DNA binding
    		•  0.397111874492592 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.297808510495986 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.256518766904171 bayes_pls_golite062009
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle