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Protein Overview: CG7849-PB

General Information:
Name(s) found: CG7849-PB / FBpp0085330 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG7849 (CG7849, FBgn0033060). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:1964415..1965593. It has the cytological map location 42A9. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: RNA binding; pseudouridine synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: RNA processing; pseudouridine synthesis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 317 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: pseudouridine synthesis [IEA]
    RNA processing [IEA]
    Molecular Function: RNA binding [IEA]
    pseudouridine synthase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTKVYDAA TVFKHMNGIL NVYKPSGMKV KHVRNAILSN ICKGLNEMEQ RKPRKLQENI  60
   61 SLLGTGTAAD HVLHNIGEQT DLSDHLLSTG PRYLPRDLIC TTVSSLGDHT SGVLLFGINR 120
  121 GAGQSSSIRK NRPVRVYHLI GHLGIATENN LPDSRVIMRS NHRHVSADRI SSLAASMQAS 180
  181 HQRKMFELCG VDLQTQEAYE LACRGLLRPA DDSQPVVYGI KLIHFDRPHF TLELHAINET 240
  241 QEYLATLVHD MALDLRTVAH CSQLRCVRHA HFDVTDSLLR HAWHLPGIIK NLRQQRDILR 300
  301 AHPQLLRQQR VELRATD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..317] PSI-BLAST 70.69897 Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.49175104308599 bayes_pls_golite062009
  • isomerase activity
    		•  0.87098451300632 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  0.86450504855635 bayes_pls_golite062009
  • pseudouridine synthase activity
    		•  0.86297783328106 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle